2019-2023年四川省天府新区直管区手足口病及其病原学特征分析  

Epidemiological and etiological characteristics of hand-foot-mouth disease in Tianfu New Area of Sichuan Province from 2019 to 2023

作　　者：许烈英 叶家利 苟艳姝 李淋 曾柯涵 邱乐平[2] XU Lieying;YE Jiali;GOU Yanshu;LI Lin;ZENG Kehan;QIU Leping(Public Health Center of Tianfu New Area,Chengdu 610213,Sichuan Province,China;Sichuan Center for Disease Control and Prevention,Chengdu 610041,Sichuan Province,China)

机构地区：[1]四川天府新区公共卫生中心,成都610213 [2]四川省疾病预防控制中心,成都610041

出　　处：《预防医学情报杂志》2024年第8期938-944,共7页Journal of Preventive Medicine Information

摘　　要：目的了解四川省天府新区直管区手足口病流行规律及病原学特征,为更好地预防和控制手足口病的发生与发展提供科学依据。方法收集2019—2023年四川省天府新区直管区手足口病病例资料,利用SPSS 22.0软件,运用描述性流行病学方法进行统计分析,检验水准为α=0.05。结果2019—2023年四川省天府新区直管区临床和确诊手足口病病例7485例,年均发病率为192.31/10万,不同年度发病率差异有统计学意义(χ^(2)=582.121,P<0.001);每年有1~2个流行高峰,主要集中在5至7月和10至12月;男女性别比为1.30∶1,差异有统计学意义(χ^(2)=74.695,P<0.001);年龄以0~5岁儿童为主,占总病例数91.76%;职业以散居儿童和托幼儿童为主,其中散居儿童4301例(57.46%),托幼儿童2703例(36.11%);年均发病率居前3位的街道依次为万安(342.45/10万)、华阳(308.32/10万)和正兴(138.24/10万),各街道发病率差异有统计学意义(χ^(2)=1920.934,P<0.001);病原学结果显示,以其他肠道病毒为主(87.66%),CV A16和EV 71分别为10.71%和1.62%。结论针对天府新区直管区手足口病发病时间、人群和地区特点,以及病原学特征,应加强发病高峰时段、散居和幼托儿童监护人的健康教育,加强人口密集社区和幼托机构防控,进一步对优势毒株其它肠道病毒进行分型,以明确病原谱和降低手足口病的发病率。Objective To understand the epidemic rules and etiology characteristics of hand-foot-mouth disease(HFMD)in Tianfu New Area,Sichuan Province,and to provide scientific basis for better preventing and controlling the occurrence and development of HFMD.Methods The case data of HFMD in Tianfu New Area,Sichuan Province from 2019 to 2023 were collected,and statistical analysis was conducted by descriptive epidemiological methods with SPSS 22.0.The test level wasα=0.05.Results From 2019 to 2023,a total of 7485 clinical and confirmed HFMD cases were reported in Tianfu New Area of Sichuan Province,with an average annual incidence rate of 192.31/105.There was a significant difference in the incidence rate among different years(χ^(2)=582.121,P<0.001).There were 1 to 2 epidemic peaks every year,mainly concentrated in May-July and October-December.The male-to-female sex ratio was 1.30∶1,and the difference was statistically significant(χ^(2)=74.695,P<0.001).The majority of cases were children aged 0-5 years,accounting for 91.76%of the total number of cases.The occupations were mainly scattered children and nursery children,and there were 4301(57.46%)scattered children and 2703(36.11%)nursery children.The top three streets in terms of average annual incidence rate were Wan'an(342.45/105),Huayang(308.32/105)and Zhengxing(138.24/105).There were significant differences in the incidence rate among different streets(χ^(2)=1920.934,P<0.001).The etiological results showed that,other enteroviruses(87.66%)were predominant,and CVA16 and EV 71 accounted for 10.71%and 1.62%,respectively.Conclusions According to the onset time,population and regional characteristics,as well as etiological characteristics of HFMD in Tianfu New Area,health education should be strengthened among scattered and childcare children's guardians in the peak period of incidence,prevention and control in densely populated communities and childcare institutions should be strengthened,and other dominant strains of enteroviruses should be further classified to clari

关 键 词：手足口病 流行病学 病原学 

分 类 号：R512.5[医药卫生—内科学]