中国大陆乙脑病原学研究的历史与现状  

The History and Current Status of Japanese Encephalitis Pathogen Research in Chinese Mainland

作　　者：梁国栋[1] LIANG Guodong(National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)

机构地区：[1]中国疾病预防控制中心病毒病预防控制所,传染病溯源预警与智能决策全国重点实验室,北京102206

出　　处：《病毒学报》2024年第4期671-678,共8页Chinese Journal of Virology

基　　金：国家重点研发计划资助(项目号:2022YFC2305304),题目:急性自然疫源性传染病病原体基因组和关键甄别位点参比数据库的建立;国家自然科学基金重大项目(项目号:81290342),题目:蚊虫携带人类病原体的发现与分离鉴定,分布特点,遗传进化规律及其与人类病毒的关系。

摘　　要：乙脑病毒为黄病毒科病毒,通过蚊虫叮咬而感染人畜动物,引起巨大公共卫生负担。我国自20世纪40年代即分离到乙脑病毒,此后在病毒分离、传播媒介、疫苗研发等方面开展大量研究,取得极大进展。本文在回顾我国乙脑病毒研究历史和研究现状基础上提出我国乙脑病毒研究存在的问题以及今后的研究内容等,以推动我国乙脑病毒研究进一步发展。Japanese encephalitis virus(JEV)is a virus belonging to the family Flaviviridae,which infects human and animals through mosquito bites,causing a huge public health burden.JEVs has been isolated in China since the 1940s.Since then,a large number of studies have been carried out in virus isolation,transmission vector,JE vaccine,and some of the research results are in the international leading level.Based on the review of the history and present of JEV research in China,this paper puts forward the shortage of research and the future on JEV research in China,so as to promote the development of JEV research in China.

关 键 词：乙脑病毒 乙脑 蚊虫 乙脑疫苗 病毒感染机理 

分 类 号：R373.3[医药卫生—病原生物学]