半夏厚朴汤治疗抑郁症研究进展  

Research Progress of Banxia Houpu Decoction (半夏厚朴汤)in the Treatment of Depression

作　　者：  全丽芳 王耀瑭  王丽莉[2] LAM Yatsu;ISHIKAWA Aki;QUAN Lifang;WANG Yaotang;WOON Pohlock;WANG Lily(International Education College of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Traditional Medicine Department of Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Yue Yang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Inner Mongolia Medical University,Inner Mongolia People's Hospital,Hohhot 010110,Inner Mongolia,China)

机构地区：[1]上海中医药大学国际教育学院,上海201203 [2]上海中医药大学附属曙光医院传统医学科,上海201203 [3]上海中医药大学附属岳阳医院,上海201203 [4]内蒙古医科大学,内蒙古呼和浩特手010110

出　　处：《贵州中医药大学学报》2024年第4期73-78,共6页Journal of Guizhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(81973770);上海市进一步加快中医药事业发展三年行动计划建设项目(ZY[2018-2020]-FWTX-7005)。

摘　　要：《金匮要略》中记载半夏厚朴汤由半夏,厚朴,紫苏,生姜,茯苓所组成,其病机多与气滞血瘀有关,常用于治疗多种消化系统疾病,其中包括抑郁症,失眠,呼吸系统疾病,反流性食管炎等。还可用于呼吸系统疾病如冠心病,慢性支气管炎和肺心病的治疗,效果明显。近年来,随着社会生活节奏的日益加快和人们生活压力以及各种精神紧张因素的增加,使抑郁症的发病率逐年上升。目前的研究发现抑郁情绪和个体的心理状态有着密切的关系,精神心理因素是抑郁情绪的一个重要组成部分。表现为情绪低落,思维迟缓,意志消沉等抑郁症状。近年来有更多研究认为职业倦怠是抑郁产生的重要因素。随着社会进步与教育水平提升,职业紧张性抑郁症患病率呈显著增长态势。半夏厚朴汤有疏肝理气,健脾燥湿,化痰祛瘀的作用。目前关于半夏厚朴汤治疗抑郁症及作用机制的研究较少,且缺乏系统性总结。本研究旨在探讨半夏厚朴汤在抑郁症流行病学及中医认知方面的应用,深入剖析近年来药理作用研究进展,为临床治疗抑郁症提供更多新思路。It is recorded in Essential Prescriptions of the Golden Coffer that Banxia Houpu decoction is composed of Banxia, Houpu, Zi Su, Gan Jiang and Fu Ling. Its pathogenesis is mostly related to qi stagnation and blood stasis, and is often used to treat a variety of digestive system diseases, including but not limited to depression, insomnia, respiratory disease, reflux Esophagitis, and etc. And it also can be used for the treatment of respiratory diseases, such as coronary heart disease, chronic bronchitis and pulmonary heart disease with obvious effect. In recent years, with the accelerating pace of social life, the increasing pressure of people's life and other various mental tension factors, the incidence rate of depression has increased year by year. The current research showed a close relationship between depressive emotions and individual psychological states. Psychological factors are an important part of depressive emotions. Low mood, delayed thinking, and low spirits are symptoms caused by depression. In recent years, more studies have suggested that job burnout is an important factor in the development of depression. With the progress of society and the improvement of education level, the incidence of occupational stress depression is showing a significant growth trend. Banxia Houpu decoction has the effects of soothing liver and regulating qi, tonifying spleen and eliminating dampness, dispelling stasis and transforming phlegm. At present, there is little research on the improvement mechanism of Banxia Houpu decoction in treating depression, and there is a lack of systematic summary. The purpose of this study is to discuss the application of Banxia Houpu decoction in the epidemiology of depression and the cognition of traditional Chinese medicine, to further analyze the research progress of pharmacological effects in recent years so as to provide more new ideas for clinical treatment of depression.

关 键 词：半夏厚朴汤 抑郁症 经方 中医治疗 研究进展 

分 类 号：R277.7[医药卫生—中医学]