滋阴化瘀法治疗妊娠晚期羊水偏少临床观察  

Clinical Effect of Nourishing Yin and Removing Blood Stasis Method on Oligohydramnios in The Third Trimester of Pregnancy

作　　者：侯红红 李俊果 刘秀志 HOU Honghong;LI Junguo;LIU Xiuzhi(Hengshui Maternal and Child Health Hospital,Hengshui 053000,Hebei,China;Hengshui Hospital of Traditional Chinese Medicine,Hengshui 053000,Hebei,China)

机构地区：[1]衡水市妇幼保健院,河北衡水053000 [2]衡水市中医医院,河北衡水053000

出　　处：《辽宁中医杂志》2024年第8期78-81,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：河北省中医药管理局科研计划项目(2022626)。

摘　　要：目的探讨滋阴化瘀法治疗妊娠晚期羊水偏少的临床效果。方法随机将60例2021年9月—2022年9月该院收治的妊娠晚期羊水偏少患者分为对照组(30例)和治疗组(30例)。对照组给予常规治疗,治疗组在对照组基础上给予滋阴化瘀法进行治疗,两组均持续治疗4周,并随访至分娩结束。比较两组治疗4周后的疗效,治疗前、治疗4周后羊水、胎盘血液灌注情况、性激素水平,治疗前、治疗1、4周后的中医证候评分,分娩结束时的新生儿窒息情况及随访期间的妊娠结局。结果治疗4周后,治疗组总有效率为90.00%(27/30),高于对照组的66.67%(20/30)(P<0.05)。与治疗前比较,治疗1、4周后,两组中医证候评分均呈逐渐降低趋势,且治疗组治疗1、4周后的中医证候评分均低于对照组(P<0.05)。与治疗前比较,治疗4周后,两组AFI及血清雌激素(E_(2))、前列腺素E(PGE)水平均升高,治疗组高于对照组(P<0.05);两组肾动脉收缩期最大血流速度/舒张期末血流速度(S/D)、脐动脉S/D及血清孕酮(P)水平均降低,治疗组低于对照组(P<0.05)。分娩结束时,治疗组新生儿窒息发生率为3.33%(1/30),低于对照组的23.33%(7/30)(P<0.05)。随访期间,治疗组不良妊娠发生率为6.67%(2/30),低于对照组的26.67%(8/30)(P<0.05)。结论滋阴化瘀法可有效调节妊娠晚期羊水偏少患者性激素水平,改善羊水、胎盘血液灌注情况及中医证候,进而可减少新生儿窒息情况的发生,改善妊娠结局,疗效显著。Objective To investigate the clinical effect of nourishing Yin and removing blood stasis method on oligohydramnios in the third trimester of pregnancy.Methods Sixty patients with oligohydramnios in the third trimester of pregnancy admitted to the hospital from September 2021 to September 2022 were divided into the control group(30 cases)and the treatment group(30 cases)according to the method of random number table.The control group was given routine treatment,and the treatment group was given the nourishing Yin and removing blood stasis method on the basis of the control group.Both groups were treated for 4 weeks,and were followed up until the end of delivery.The curative effect after 4 weeks of treatment,the amniotic fluid,placental blood perfusion situation and levels of sex hormones before and after 4 weeks of treatment,the scores of traditional Chinese medicine symptom before treatment and after 1 and 4 weeks of treatment,the neonatal asphyxia at the end of delivery and the pregnancy outcome during the followed up period of the two groups were compared.Results The total effective rate in the treatment group was 90.00%(27/30),higher than 66.67%(20/30)in the control group after 4 weeks of treatment(P<0.05).Compared with those before treatment,after 1 and 4 weeks of treatment,the scores of traditional Chinese medicine symptoms of the two groups showed a gradually decreasing trend,and the scores of traditional Chinese medicine symptoms of the treatment group after 1 and 4 weeks of treatment were lower than those of the control group(P<0.05).Compared with those before treatment,after 4 weeks of treatment,the levels of amniotic fluid index(AFI),serum estrogen(E_(2))and prostaglandin E(PGE)in the two groups increased,and those in the treatment group were higher than those in the control group(P<0.05).The maximum systolic blood flow velocity of renal artery/end diastolic blood flow velocity(S/D),umbilical artery S/D and level of serum progesterone(P)in the two groups decreased,and those in the treatment group were l

关 键 词：妊娠晚期 羊水偏少 滋阴化瘀法 中医证候 羊水指数 性激素 新生儿窒息 

分 类 号：R271.41[医药卫生—中医妇科学]