益气通络、健脾补肾法联合穴位贴敷在慢性阻塞性肺疾病稳定期患者中的应用效果  

Application Effect of Method of Invigorating Qi and Dredging Collateral,Invigorating Spleen and Tonifying Kidney Combined with Acupoint Application in Patients with Chronic Obstructive Pulmonary Disease at Stable Stage

作　　者：辛元元 袁胜利 佟珺 罗静 崔朦 XIN Yuanyuan;YUAN Shengli;TONG Jun;LUO Jing;CUI Meng(Zhangjiakou Hospital of Traditional Chinese Medicine,Zhangjiakou 075001,Hebei,China)

机构地区：[1]张家口市中医院,河北张家口075001

出　　处：《辽宁中医杂志》2024年第8期82-86,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：中医药类科学研究课题计划项目(2023191)。

摘　　要：目的探讨益气通络、健脾补肾法联合穴位贴敷在慢性阻塞性肺疾病(简称慢阻肺)稳定期患者中的应用效果。方法采用随机数字表法将于2020年1月—2021年12月在河北省张家口市中医院接受治疗的180例慢阻肺稳定期患者分为A组、B组和C组,各60例。3组均给予常规西医治疗,A组给予穴位贴敷治疗,B组给予益气通络、健脾补肾方治疗,C组给予益气通络、健脾补肾法联合穴位贴敷治疗。3组均持续治疗9个月。比较治疗9个月后的临床疗效,治疗前、治疗9个月后的6min步行距离(6 min walking distance,6MWD)、劳累程度、生活质量、呼吸困难指数、血气指标及炎性因子。结果治疗9个月后,C组总有效率为88.33%(53/60),高于A、B组的55.00%(33/60)、73.00%(44/60),B组高于A组(P<0.05)。与治疗前比较,治疗9个月后,3组6 MWD均延长,且C组长于A、B组,B组长于A组;劳累评估量表(Borg)评分、慢阻肺患者评估测试(COPD patient assessment test,CAT)评分、改良英国医学研究会呼吸困难指数(modified British medical research council,mMRC)、动脉血二氧化碳分压(PaCO_(2))、血清白细胞介素-8(interleukin-8,IL-8)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)及C反应蛋白(C-reactive protei,CRP)水平均降低,且C组低于A、B组,B组低于A组;3组血氧饱和度(SpO_(2))、动脉血氧分压(PaO_(2))均升高,且C组高于A、B组,B组高于A组(P<0.05),而3组酸碱度(pH)治疗前后及组间比较,差异无统计学差异(P>0.05)。结论益气通络、健脾补肾法联合穴位贴敷可有效缓解慢阻肺稳定期患者呼吸困难症状,减轻患者劳累程度及炎症反应,并改善患者血气指标,提高患者步行能力及生活质量,进而提高治疗效果。Objective To explore the application effect of the method of invigorating Qi and dredging collateral,invigorating spleen and tonifying kidney combined with acupoint application in patients with chronic obstructive pulmonary disease(COPD)at stable stage.Methods A total of 180 patients with COPD in stable stage who were treated in Zhangjiakou Hospital of Traditional Chinese Medicine in Hebei Province from January 2020 to December 2021 were divided into the group A,the group B and the group C(60 cases)by random number table method,60 patients in each group.The three groups were treated with conventional western medicine.The group A was treated with acupoint application,the group B was treated with Yiqi Tongluo,Jianpi Bushen Recipe(益气通络、健脾补肾方)and the Group C was treated with the method of invigorating Qi and dredging collateral,invigorating spleen and tonifying kidney combined with acupoint application.The three groups were treated for 9 months.The clinical effects after 9 months of treatment,including 6 min walking distance(6MWD),fatigue degree,quality of life,dyspnea index,blood gas index and inflammatory factors before and after 9 months of treatment between two groups were compared.Results After 9 months of treatment,the rate of total effective of the group C was 88.33%(53/60),higher than 55.00%(33/60)and 73.00%(44/60)of the group A and B,and that of the group B was higher than that of the group A(P<0.05).Compared with that before treatment,after 9 months of treatment,the 6 MWD of the three groups was prolonged,and the 6 MWD of the group C was longer than that of the group A and B,and the 6 MWD of the group B was longer than that of the group A.The scores of fatigue assessment scale(Borg),COPD patient assessment test(CAT)and modified British medical research council(mMRC),arterial partial blood pressure of carbon dioxide(PaCO_(2)),the levels of serum interleukin-8(IL-8),tumor necrosis factor-α(TNF-α)and C-reactive protein(CRP)in three groups decreased,and the indexes in the group C were lowe

关 键 词：慢阻肺 穴位贴敷 益气通络、健脾补肾法 血气指标 炎性因子 

分 类 号：R256.1[医药卫生—中医内科学]