17例猴痘患者临床特征分析  

Clinical characteristics of 17 patients with monkeypox

作　　者：何耀钦 黄美祯 刘骏 梁婷婷 冯凤泉 李倩 李莎[1] 何朝永 HE Yao-qin;HUANG Mei-zhen;LIU Jun;LIANG Ting-ting;FENG Feng-quan;LI Qian;LI Sha;HE Chao-yong(Department of Internal Medicine,The Fourth People’s Hospital of Nanning,Nanning 530023,China;Department of Laboratory Medicine,The Fourth People’s Hospital of Nanning,Nanning 530023,China)

机构地区：[1]南宁市第四人民医院内科,广西南宁530023 [2]南宁市第四人民医院检验科,广西南宁530023

出　　处：《中国感染控制杂志》2024年第8期1007-1011,共5页Chinese Journal of Infection Control

基　　金：南宁市科学研究与技术开发计划课题(20213025-4);广西壮族自治区卫生健康委员会自筹经费科研课题(Z20201108)。

摘　　要：目的分析猴痘患者的流行病学及临床特征。方法采用回顾性方法收集2023年7—10月在南宁市某院住院治疗的17例猴痘患者资料,对流行病学史、临床表现、实验室检查、治疗及预后情况进行分析总结。结果17例患者均为男性,中位年龄28岁,其中15例(88.2%)发病前21 d内有男男性行为。主要临床表现为皮疹、发热,皮疹主要分布于肛门、会阴及生殖器(82.4%),其次为躯干和四肢(52.9%)、头面部(35.3%),足底和手掌较少见,部分患者存在腹股沟淋巴结肿大。所有患者均病情好转出院,平均住院时间7 d。结论广西南宁地区猴痘的传播流行以男性性接触人群居多,以发热、皮疹为核心症状,所有患者病情均较轻,预后好。Objective To analyze the epidemiological and clinical characteristics of patients with monkeypox.Methods Data of 17 patients with monkeypox hospitalized in a hospital in Nanning City from July to October 2023 were collected retrospectively.The epidemiological history,clinical manifestations,laboratory examinations,treatment and prognosis were analyzed and summarized.Results All 17 patients were male,with a median age of 28 years old.Fifteen(88.2%)patients were men who had sex with men(MSM)within 21 days prior to onset.Major clinical manifestations were rash and fever.Rashes distributed mainly in the anus,perineum and genitals(82.4%),followed by the trunk and limbs(52.9%),head and face(35.3%),while soles and palms were rare.Some patients had swollen inguinal lymph nodes.All patients were discharged from hospital after improvement,with an average hospital stay of 7 days.Conclusion The monkeypox epidemic in Nanning area of Guangxi occurs mainly in MSM population,with fever and rashes as the major symptoms.All patients have mild disease and good prognosis.

关 键 词：猴痘 流行病学 临床特征 男男性行为 MSM 

分 类 号：R181.8[医药卫生—流行病学] R511[医药卫生—公共卫生与预防医学]