HIV感染者/AIDS患者疾病接受度现状及相关因素研究  

Disease acceptance in HIV/AIDS patients and related factors

作　　者：秦子琪 曹桂英 谢建平 王笑 李怡轩 陆乔悦 王红红[1] 肖雪玲[1] QIN Zi-qi;CAO Gui-ying;XIE Jian-ping;WANG Xiao;LI Yi-xuan;LU Qiao-yue;WANG Hong-hong;XIAO Xue-ling(Xiangya Nursing School,Central South University,Changsha 410013,China;The First Hospital of Changsha,Changsha 410005,China)

机构地区：[1]中南大学湘雅护理学院,湖南长沙410013 [2]长沙市第一医院,湖南长沙410005

出　　处：《中国感染控制杂志》2024年第8期1016-1022,共7页Chinese Journal of Infection Control

基　　金：国家自然科学基金项目(82204169);湖南省自然科学基金项目(2023JJ40787)。

摘　　要：目的了解人类免疫缺陷病毒(HIV)感染者/艾滋病(AIDS)患者疾病接受度现状及其相关因素,以指导临床制定干预措施,并为改善其临床结局提供实证依据。方法采用便利抽样法选取在某医院AIDS定点治疗门诊接受治疗的555例HIV感染者/AIDS患者,收集研究对象的一般资料、疾病接受度、疾病自我管理效能和临床结局(即生活质量、CD4+T淋巴细胞计数、HIV病毒载量)。结果HIV感染者/AIDS患者疾病接受度平均为(26.08±5.34)分。多元线性回归分析结果显示,宗教信仰、疾病自我管理效能是影响患者疾病接受度的相关因素(均P<0.05),可解释HIV感染者/AIDS患者疾病接受度30.4%的变异,且患者的疾病接受度与其生活质量紧密相关(P<0.001)。结论HIV感染者/AIDS患者的疾病接受度处于中等水平。在临床工作中医务人员应充分考虑患者的宗教信仰情况和疾病自我管理效能水平,以制定针对性的干预措施,提高患者疾病接受度,从而进一步促进患者获得更高的生活质量。Objective To understand the disease acceptance status and related factors in human immunodeficiency virus(HIV)-infected/acquired immunodeficiency syndrom(AIDS)patients,so as to guide the clinical development of intervention measures,and to provide empirical evidence for improving clinical outcomes.Methods Convenience sampling method was used to select 555 HIV-infected/AIDS patients who received treatment in the designated AIDS treatment clinic of a hospital.General data,disease acceptance,disease self-management efficacy and clinical outcomes(such as quality of life,CD4+T lymphocyte count and HIV viral load)of the studied subjects were collected.Results The average disease acceptance of HIV-infected/AIDS patients was(26.08±5.34)points.Multiple linear regression analysis showed that religious belief and self-management efficacy were related factors affecting the di-sease acceptance of patients(both P<0.05),which could explain the 30.4%variation in disease acceptance of HIV-infected/AIDS patients,and the disease acceptance of patients was closely related to their quality of life(P<0.001).Conclusion HIV-infected/AIDS patients have a moderate level of disease acceptance.Medical staff should fully consider patients’religious beliefs and self-management efficacy,so as to formulate targeted intervention mea-sures to improve patients’acceptance of disease,and further promote patients’quality of life.

关 键 词：人类免疫缺陷病毒 艾滋病 疾病接受度 临床结局 生活质量 

分 类 号：R181.3[医药卫生—流行病学] R512.91[医药卫生—公共卫生与预防医学]