电针治疗尼古丁依赖的疗效观察  

Observation on the efficacy of electroacupuncture in the treatment of nicotine dependence

作　　者：夏心瑀 李爱林 戴然然[3] 卫平[4] 周剑平[3] 曹世杰 姚栩靖 梁艳 XIA Xinyu;LI Ailin;DAI Ranran;WEI Ping;ZHOU Jianping;CAO Shijie;YAO Xujing;LIANG Yan(Yueyang Hospital of Integrative Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China;Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China;Shanghai Pulmonary Hospital,Shanghai 200433,China;Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437 [2]上海中医药大学,上海201203 [3]上海交通大学医学院附属瑞金医院,上海200025 [4]上海市肺科医院,上海200433 [5]上海中医药大学附属龙华医院,上海200032

出　　处：《上海针灸杂志》2024年第8期864-869,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：国家自然科学基金青年项目(81403473);上海中医药大学外籍研究生教育研究课题(JY611.06.35.02);上海市十三五临床重点专科项目(shslczdzk04701);高水平研究型中医医院建设项目(YC-2023-0901)。

摘　　要：目的观察电针治疗尼古丁依赖的临床疗效。方法将60例尼古丁依赖者用随机数字表法分为电针组和对照组,每组30例。对照组采用口服酒石酸伐尼克兰片治疗,电针组予电针治疗。分别于治疗前以及治疗第3天、治疗第1周、治疗第2周、治疗第3周、治疗第4周和第16周随访时,观察两组吸烟量、烟草依赖评估量表(fagerstorm test for nicotine dependence,FTND)、吸烟严重度指数(heaviness of smoking index,HSI)、吸烟渴求简短问卷(brief questionnaire of smoking urges,QSU-Brief)和明尼苏达尼古丁戒断症状量表(Minnesota nicotine withdrawal scale,MNWS)评分的变化。结果治疗第4周及第16周随访时,两组吸烟量、FTND、HSI、QSU-Brief和MNWS的评分均较治疗前降低(P<0.05)。治疗第3天以及治疗第1、第2和第3周,电针组吸烟量评分低于对照组(P<0.05);治疗第4周,两组吸烟量评分比较,差异无统计学意义(P>0.05)。治疗第3天以及治疗第1、第2和第3周,电针组QSU-Brief评分低于对照组(P<0.05);治疗第4周及第16周随访时,两组QSU-Brief评分比较,差异无统计学意义(P>0.05)。结论电针可改善尼古丁依赖者的戒断症状,临床疗效优于口服酒石酸伐尼克兰片,电针疗效的累积效应与时间呈正相关。Objective To observe the clinical efficacy of electroacupuncture in the treatment of nicotine dependence.Method A total of 60 cases of nicotine dependence were divided into an electroacupuncture group and a control group using the random number table method,with 30 cases in each group.The control group was treated with oral Varenicline tartrate tablets,while the electroacupuncture group was treated with electroacupuncture.The changes of smoking amount,fagerstorm test for nicotine dependence(FTND),heaviness of smoking index(HSI),brief questionnaire of smoking urges(QSU-Brief),and Minnesota nicotine withdrawal scale(MNWS)scores in both groups were observed before treatment,on the 3rd day,in the 1st week,2nd week,3rd week,4th week of treatment and the 16th week of follow-up respectively. Result In the 4th week of treatment and 16th week of follow-up, the scores of smoking, FTND, HSI, QSU-Brief, and MNWS were lower in both groups compared with the pre-treatment scores (P<0.05). On the 3rd day of treatment as well as in the 1st week, 2nd week and 3rd week of treatment, the smoking score of the electroacupuncture group was lower than that of the control group (P<0.05);in the 4th week of treatment, the difference between the smoking scores of the two groups was statistically insignificant (P>0.05). The QSU-Brief scores of the electroacupuncture group were lower than those of the control group on the 3rd day of treatment and in the 1st week, 2nd week and 3rd week of treatment (P<0.05);the differences were not statistically significant when comparing the QSU-Brief scores of the two groups in the 4th week of treatment and 16th week of follow-up (P>0.05). Conclusion Electroacupuncture can improve the withdrawal symptoms of nicotine dependents, the clinical efficacy is better than oral Varenicline tartrate tablets, and the cumulative effect of electroacupuncture efficacy is positively correlated with time.

关 键 词：针刺疗法 电针 物质戒断综合征 尼古丁依赖 吸烟 成瘾 

分 类 号：R246.6[医药卫生—针灸推拿学]