2型糖尿病男性患者血脂、体重指数与性功能障碍的关系  

Relationship Between Blood Lipid,Body Mass Index and Sexual Dysfunction in Male Patients with Type 2 Diabetes Mellitus

作　　者：刘洋 张博 何小景 刘华朋 王松[1] 薛榜稳 周倩 索亚男 褚桂克[1] 曹欢 杨万顺 路怡芳 LIU Yang;ZHANG Bo;HE Xiaojing;LIU Huapeng;WANG Song;XUE Bangwen;ZHOU Qian;SUO Yanan;CHU Guike;CAO Huan;YANG Wanshun;LU Yifang(Department of Endocrinology,Nanyang Central Hospital,Nanyang 473000,China;Department of Cardiology,Nanyang Central Hospital,Nanyang 473000,China;Department of Thyroid and Breast Surgery,Nanyang First People’s Hospital,Nanyang 473000,China)

机构地区：[1]南阳市中心医院内分泌科,河南南阳473000 [2]南阳市中心医院心内科,河南南阳473000 [3]南阳市第一人民医院甲状腺乳腺外科,河南南阳473000

出　　处：《河南医学研究》2024年第15期2739-2743,共5页Henan Medical Research

摘　　要：目的探究男性2型糖尿病患者血脂、体重指数(BMI)与性功能障碍的关系。方法选取南阳市中心医院2020年6月至2023年6月接诊的男性2型糖尿病患者252例,收集患者的临床资料,检测患者入院时的血脂相关指标水平及BMI,根据病历复查结果随访,记录患者性功能障碍的发生率,分为性功能障碍组和正常组,筛查男性2型糖尿病患者发生性功能障碍的影响因素,评估血脂相关指标及BMI对男性2型糖尿病患者发生性功能障碍的预测价值。结果截至随访结束,252例患者中失访11例,有效随访率为95.63%。剩余241例患者中确诊性功能障碍163例,发生率为67.63%。性功能障碍组合并高血压占比及抑郁程度评分、BMI、总胆固醇(TC)、甘油三酯(TG)及低密度脂蛋白胆固醇(LDL-C)均高于性功能正常组(P<0.05),睾酮低于性功能正常组(P<0.05)。logistic分析结果显示,合并高血压、抑郁程度评分、BMI、TC、TG、LDL-C是男性2型糖尿病患者发生性功能障碍的危险因素(P<0.05),睾酮是男性2型糖尿病患者发生性功能障碍的保护因素(P<0.05)。受试者工作特征曲线分析显示,BMI、TC、TG、LDL-C单一及联合预测男性2型糖尿病患者发生性功能障碍的曲线下面积分别为0.764(95%CI:0.705~0.853)、0.810(95%CI:0.745~0.876)、0.735(95%CI:0.657~0.812)、0.759(95%CI:0.693~0.836)、0.872(95%CI:0.817~0.927)。结论BMI、TC、TG、LDL-C与男性2型糖尿病患者发生性功能障碍有关,且可用于男性2型糖尿病患者并发性功能障碍的预测。Objective To explore the relationship between blood lipid,body mass index(BMI)and sexual dysfunction in male patients with type 2 diabetes mellitus.Methods A total of 252 male patients with type 2 diabetes were selected from Nanyang Central Hospital from June 2020 to June 2023.Clinical data of the patients were collected,the levels of lipids and BMI of the patients at admission were detected,and the incidence of sexual dysfunction of the patients was recorded according to the results of medical records review.The influencing factors of sexual dysfunction in male patients with type 2 diabetes were screened,and the predictive value of lipid-related indexes and BMI for sexual dysfunction in male patients with type 2 diabetes was evaluated.Results By the end of follow-up,11 cases of 252 patients were lost to follow-up,and the effective follow-up rate was 95.63%.Among the remaining 241 patients,163 were diagnosed with sexual dysfunction(67.63%).The proportion of hypertension,depression score,BMI,total cholesterol(TC),triglycerides(TG)and low-density lipoprotein cholesterol(LDL-C)in sexual dysfunction group were higher than those in normal sexual function group(P<0.05),and testosterone was lower than that in normal sexual function group(P<0.05).Logistic analysis showed that combined hypertension,depression degree score,BMI,TC,TG and LDL-C were risk factors for sexual dysfunction in male type 2 diabetes patients(P<0.05),and testosterone was protective factor for sexual dysfunction in male type 2 diabetes patients(P<0.05).Receiver operating characteristic curve analysis showed that the area under the curve of BMI,TC,TG,LDL-C single and combined prediction of sexual dysfunction in male type 2 diabetes patients were 0.764(95%CI:0.705-0.853),0.810(95%CI:0.745-0.876),0.735(95%CI:0.657-0.812),0.759(95%CI:0.693-0.836)and 0.872(95%CI:0.817-0.927).Conclusion BMI,TC,TG and LDL-C are related to sexual dysfunction in men with type 2 diabetes,and can be used to predict sexual dysfunction in men with type 2 diabetes.

关 键 词：2型糖尿病 性功能障碍 男性 血脂 体重指数 预测 

分 类 号：R698[医药卫生—泌尿科学]