不同模式经颅磁刺激治疗神经病理性疼痛的研究进展  

Application of different modes of transcranial magnetic stimulation for neuropathic pain

作　　者：吴思杏 纪运 马柯[1] WU Si-xing;JI Yun;MA Ke(Department of Pain,Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China)

机构地区：[1]上海交通大学医学院附属新华医院疼痛科,上海200092

出　　处：《中国疼痛医学杂志》2024年第8期563-567,共5页Chinese Journal of Pain Medicine

基　　金：国家自然科学基金面上项目(82371224);上海交通大学“交大之星*重点项目”(20230103)。

摘　　要：神经病理性疼痛是由于躯体感觉系统的损害或疾病引起的疼痛,其发生机制可能与伤害性感受器敏化、传入神经元异常的异位兴奋性、脊髓后角促伤害感受的易化等有关。经颅磁刺激是一种无创、非侵入性的治疗神经病理性疼痛的手段,可以有效缓解疼痛。本文就经颅磁刺激治疗神经病理性疼痛的可能机制、不同模式的临床应用、安全性等方面进行综述,旨在为进一步研究经颅磁刺激治疗神经病理性疼痛提供参考及理论依据。Neuropathic pain is caused by a lesion or disease to the somatosensory nervous system,and its mechanism may be related to sensitization of injury receptors,abnormal ectopic excitability of afferent neurons,and vulnerability of the posterior horn of the spinal cord to injury perception.Transcranial magnetic stimulation is a noninvasive treatment for neuropathic pain and can effectively relieve pain.This article reviews and introduces the possible mechanisms,clinical application of different modalities,and safety of transcranial magnetic stimulation for the treatment of neuropathic pain,aiming to provide reference and theoretical basis for further research on the treatment of neuropathic pain with transcranial magnetic stimulation.

关 键 词：经颅磁刺激 神经病理性疼痛 重复经颅磁刺激 θ节律爆发式磁刺激 

分 类 号：R402[医药卫生—临床医学]