失血性休克复苏液体的演进——低效价抗体O型全血正重新成为首选的应急通用桥接复苏液体  

Evolution of resuscitation fluid for hemorrhagic shock——low titer group O whole blood is becoming preferred emergent universal bridging resuscitation fluid

作　　者：王鸿捷[1,2] 郭永建 WANG Hongjie;GUO Yongjian(Bejing Red Cross Blood Center,Beijing 100083,China;Sub-Committee of Blood Standards,National Committee of Health Standards;Fujian Provincial Blood Centre)

机构地区：[1]北京市红十字血液中心,北京100083 [2]国家卫生健康标准委员会血液标准专业委员会 [3]福建省血液中心

出　　处：《中国输血杂志》2024年第8期953-964,共12页Chinese Journal of Blood Transfusion

摘　　要：血液复苏是严重失血患者的关键急救措施。血液复苏液体的选用,经历了从全血到晶体液/胶体液、晶体液联合红细胞、等比例血液成分的演进过程。近20年来,采用低效价抗体O型全血(low titer group O whole blood,LTOWB)作为血液复苏的首选应急通用桥接复苏液,已发展成为大趋势。我们对全血在严重失血患者的应用历史和现状做一介绍,并提出我国采用LTOWB作为首选应急通用血液的进一步论证和验证研究建议。Timely and effective blood resuscitation is very important for patients with severe blood loss.The resuscitation fluids for hemorrhagic shock have evolved from whole blood to crystalloid/colloid solutions,crystalloid combined with red blood cells,to balanced blood components.In the past 20 years,it is a growing trend that low titer antibody group O whole blood(LTOWB)is used as the preferred universal bridging resuscitation fluid for emergent blood resuscitation.Herein we provide a review of the history and current status of whole blood for patients with severe bleeding and make a suggestion to launch a national implementation research program of LTOWB in China.

关 键 词：低效价抗体O型全血 血液复苏 严重失血 

分 类 号：R457.1[医药卫生—治疗学] R541.64[医药卫生—临床医学] R441.9