Sequence-Controlled Synthesis of Alternating Poly(ester amide)s using Water as Control Agent in One-Pot  

作　　者：Tao Liu Fang-Fang Niu Kan Cheng Yu-Min Xia Bo-Mou Ma Xue-Li Wang Jian-Yong Yu Yong He 

机构地区：[1]State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,College of Materials Science and Engineering,Donghua University,Shanghai 201620,China [2]Innovation Center for Textile Science and Technology,Donghua University,Shanghai 201620,China

出　　处：《Chinese Journal of Polymer Science》2024年第8期1015-1020,共6页高分子科学（英文版）

基　　金：financially supported by the innovation funding from Wei Qiao Group(Nos.H2872307 and H2872305);Fundamental Research Funds for the Central Universities and Graduate Student Innovation Fund of Donghua University(No.CUSF-DH-D-2024004)。

摘　　要：Poly(ester amide)s(PEAs)attract much attention as a new kind of biodegradable polymers.However,the synthesis of PEAs with sequence-regulated chain structures is still complicated due to the multistep polymerization,high monomer purity,as well as the usage of organic solvents,which greatly inhibits its development and applications.Herein,a one-pot strategy without solvent was developed to synthesize the alternating PEA fromα,ω-amino alcohol and dicarboxylic acid by sequential polycondensation,where water was used as the controlling agent for amidation and esterification.Specifically,the amidation and esterification were controlled to proceed in turn by adding or removing water,realizing the one-pot preparation of alternating PEAs.The resultant PEA is characterized by^1H-and^(13)C-NMR,and its chain structure is confirmed to be highly quasi-alternating similar to alternating PEAs prepared by classical methods The evaluations from DSC and DMA demonstrate that the properties of quasi-alternating PEA(T_(m)=102℃,ΔH_(m)=30J·g^(-1))are far superior to those of random PEA(T_(m)=72℃,ΔH_(m)<1 J·g^(-1)).

关 键 词：Biodegradable macromolecules Polymer architectures Sequence-controlled synthesis One-pot polymerization 

分 类 号：TQ317[化学工程—高聚物工业]