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作 者:张建华 刘世超 郭文姣 李娜 ZHANG Jian-hua;LIU Shi-chao;GUO Wen-jiao;LI Na(N.O.D Topia(Guangzhou)Biotechnology Co.,Ltd.,Guangzhou,Guangdong 510000,China;Simpcare(Guangzhou)Biotechnology Co.,Ltd.,Guangzhou,Guangdong 510000,China)
机构地区:[1]诺德溯源(广州)生物科技有限公司,广东广州510000 [2]溪木源(广州)生物科技有限公司,广东广州510000
出 处:《日用化学品科学》2024年第8期47-51,共5页Detergent & Cosmetics
摘 要:为研究挪威云杉叶提取物在油性皮肤护理中的应用,对其体外控油和抗炎活性进行研究,结果发现对比模型组,挪威云杉叶提取物显著降低了皮脂腺分泌脂质(p<0.05),并呈现剂量依赖性关系,同时10%挪威云杉叶提取物能够显著下降NO含量(p<0.05)。进一步制备含2.5%挪威云杉叶提取物的乳液,招募30名油性皮肤志愿者使用14天后测量其油脂含量、皮肤光泽度和亮度等参数。结果表明,使用14天后,志愿者皮肤油脂显著下降(p<0.050),与此同时,光泽度和皮肤亮度显著上升(p<0.05)。表明挪威云杉叶通过抑制皮脂腺细胞分泌脂质以及抗炎从而达到控制面部油脂分泌的效果。To investigate the application of Picea abies leaf extract in oily skin care,this paper studied in vitro oil control and antiinflammatory activities.The results showed that Picea abies leaf extract significantly reduced lipid secretion by sebaceous glands compared to the model group(p<0.05)in a dose-dependent manner.Additionally,10%concentration of Picea abies leaf extract significantly decreased nitric oxide(NO)content(p<0.05).An emulsion containing 2.5%Picea abies leaf extract was then prepared and tested on 30 volunteers with oily skin over a period of 14 days.Measurements of sebum content,skin gloss,and brightness were taken before and after the treatment.The findings indicated a significant decrease in skin sebum(p<0.05)and a significant increase in skin gloss and brightness(p<0.05)after 14 days of use.These results suggest that the Picea abies leaf extract effectively controls facial sebum secretion by inhibiting lipid production in sebaceous gland cells and through its anti-inflammatory effect.
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