基于伏痰理论探讨广泛性焦虑障碍与肠道菌群的关系及治疗  

To explore the relationship between GAD and intestinal flora and its treatment based on the latent phlegm theory

作　　者：陈佳易 陈思敏 叶吴洁 吕心怡 王雅楠 贺佳慧 王娣[2] 宋月晗 CHEN Jiayi;CHEN Simin;YE Wujie;LYU Xinyi;WANG Yanan;HE Jiahui;WANG Di;SONG Yuehan(Beijing University of Chinese Medicine,Beijing 100029;Department of Integrative Traditional Chinese and Western Psychiatry,Beijing Anding Hospital,Capital Medical University)

机构地区：[1]北京中医药大学中医学院,北京100029 [2]首都医科大学附属北京安定医院中西医结合病房

出　　处：《现代中医临床》2024年第4期83-86,共4页Modern Chinese Clinical Medicine

基　　金：国家自然科学基金面上项目(No.81874427)。

摘　　要：广泛性焦虑障碍(generalized anxiety disorder, GAD),中医在治疗该疾病方面因疗效好且不良反应小备受学界关注。中医的伏痰理论历史悠久,且从伏痰辨治精神疾病是古今中医的共同认知,所以伏痰理论的运用可以为中医治疗与痰有关的疾病开创新的思路。本文试从伏痰理论出发,结合西医学的研究热点肠道菌群,来探讨GAD这一疾病的病因病机和伏痰的现代生物学机制,寻找伏痰和GAD的相关性和共同特点。以期丰富治疗焦虑障碍类疾病的科学内涵,且找寻中医传统名方温胆汤治疗此类疾病遣方用药的理论基础,为今后GAD的防治提供理论基石。Generalized anxiety disorder(GAD)has garnered significant attention in the academic community due to the effective and low-side-effect treatments offered by traditional Chinese medicine(TCM).The Futan(latent phlegm)theory,with its long historical roots,has been a cornerstone in the diagnosis and treatment of mental illnesses in TCM.Its application can offer innovative approaches to treating phlegm-related diseases.This paper aims to explore the etiology and pathogenesis of GAD through the lens of the Futan theory,integrating modern medical research on intestinal flora,a current hot topic.By identifying the correlations and shared characteristics between GAD and latent phlegm,this study seeks to deepen the scientific understanding of anxiety disorder treatments.Additionally,it aims to establish the theoretical foundation for using the renowned TCM formula,Wendan(GallbladderWarming)Decoction,in treating such disorders.This exploration provides a theoretical basis for the future prevention and treatment of GAD.

关 键 词：GAD 伏痰理论 肠道菌群 温胆汤 

分 类 号：R259[医药卫生—中西医结合]