多次间歇冷光源光疗应用于新生儿黄疸的效果  

Effect of Multiple Intermittent Cold Light Source Phototherapy on Neonatal Jaundice

作　　者：林钦秀 陈柏希 LIN Qinxiu;CHEN Boxi(Jinjiang Maternal and Child Health Hospital,Jinjiang 362200,China;不详)

机构地区：[1]晋江市妇幼保健院,福建晋江362200

出　　处：《中外医学研究》2024年第21期41-45,共5页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨多次间歇冷光源光疗应用于新生儿黄疸的效果。方法:选取2020年7月—2023年9月晋江市妇幼保健院收治的79例新生儿黄疸患儿作为研究对象,按照随机数表法将其分为持续组和间歇组。持续组39例,给予持续性冷光源光疗;间歇组40例,给予多次间歇冷光源光疗。比较两组治疗效果、疾病转归进程、黄疸指数、胆红素水平、血液细胞变化以及不良反应发生情况。结果:两组总有效率比较,差异无统计学意义(P>0.05);间歇组胎便转黄、总胆红素(TBIL)降至正常、黄疸消退及住院时间均低于持续组,差异有统计学意义(P<0.05);间歇组在治疗24 h、48 h、72 h后的黄疸指数均低于持续组,差异有统计学意义(P<0.05);治疗72 h后,间歇组TBIL低于持续组,差异有统计学意义(P<0.05),但两组间接胆红素(IBIL)、直接胆红素(DBIL),差异无统计学意义(P>0.05);治疗72 h后,两组Hb、RBC、PLT均下降,但间歇组高于持续组,差异有统计学意义(P<0.05);间歇组不良反应较持续组少,差异有统计学意义(P<0.05)。结论:与经持续性冷光源治疗的新生儿黄疸患儿相比,多次间歇性光疗在改善高TBIL、黄疸症状方面效果更明显,能够加快疾病转归,且对血液细胞影响较小,治疗安全性更高。Objective:To investigate the effect of multiple intermittent cold light source phototherapy on neonatal jaundice.Method:79 children with neonatal jaundice admitted to the hospital from July 2020 to September 2023 were selected as the study objects and divided into two groups according to random number table method.39 cases in the continuous group and they were given continuous cold light source phototherapy.40 cases in the intermittent group and they were given multiple intermittent cold light source phototherapy.The treatment effect,disease progression,jaundice index,bilirubin level,blood cell changes and adverse reactions were compared between the two groups.Result:There was no difference in the comparation of total effective rate between the two groups(P>0.05).The yellow turn of fetal stool,TBIL decreased to normal,jaundice subsided and hospital stay in intermittent group were lower than those in continuous group(P<0.05).The jaundice index of intermittent group was lower than that of continuous group after 24h,48h and 72h treatment(P<0.05).After 72h of treatment,TBIL in intermittent group was lower than that in continuous group(P<0.05),but there was no difference in IBIL and DBIL between the two groups(P>0.05).After 72h of treatment,Hb,RBC and PLT decreased in both groups,but the intermittent group was higher than the continuous group(P<0.05).The adverse reactions in intermittent group were less than those in continuous group(P<0.05).Conclusion:Compared with neonates with jaundice treated by continuous cold light source,multiple intermittent light therapy is more effective in improving the symptoms of high TBIL and jaundice,can accelerate the outcome of the disease,and has less effect on blood cells,and has higher treatment safety.

关 键 词：冷光源光疗 新生儿黄疸 多次间歇性 黄疸指数 C反应蛋白 

分 类 号：R722.17[医药卫生—儿科]