酚磺乙胺注射液与白眉蛇毒血凝酶、维生素K_(1)联合在新生儿便血治疗中的价值  

The Value of Etamsylate Injection and Hemocoagulase and Vitamin K_(1) in the Treatment of Neonatal Hematochezia

作　　者：马娟 MA Juan(Jiangnan University Affiliated Children's Hospital,Wuxi 214121,China)

机构地区：[1]江南大学附属儿童医院(无锡市儿童医院),江苏无锡214121

出　　处：《中外医学研究》2024年第22期51-54,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析酚磺乙胺注射液与白眉蛇毒血凝酶、维生素K_(1)联合在新生儿便血治疗中的价值。方法:选取2019年10月—2022年12月江南大学附属儿童医院收治的90例新生儿便血患儿作为研究对象,按随机数表法分成两组,对照组实施酚磺乙胺注射液治疗,观察组实施酚磺乙胺注射液与白眉蛇毒血凝酶及维生素K_(1)治疗。比较两组临床疗效、不良反应发生率、炎症因子水平。结果:观察组总有效率高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。观察组白细胞介素-6(interleukin-6,IL-6)、C反应蛋白(C-reactive protein,CRP)低于对照组,白细胞介素-10(interleukin-10,IL-10)高于对照组,差异有统计学意义(P<0.05)。结论:酚磺乙胺注射液与白眉蛇毒血凝酶、维生素K_(1)联合在新生儿便血治疗中可行性较高,可以改善炎症状态,提升治疗效果和安全性。Objective:To analyze the value of Etamsylate Injection and Hemocoagulase and Vitamin K_(1) in the treatment of neonatal hematochezia.Method:A total of 90 neonatal children with hematochezia treated in Jiangnan University Affiliated Children's Hospital from October 2019 to December 2022 were selected as the study objects and divided into two groups according to random number table method.The control group was treated with Etamsylate Injection,and the observation group was treated with Etamsylate Injection and Hemocoagulase and Vitamin K_(1).The clinical efficacy,incidence of adverse reactions and levels of inflammatory factors were compared between the two groups.Result:The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).The interleukin-6(IL-6)and C-reactive protein(CRP)levels in the observation group were lower than those in the control group,and the interleukin-10(IL-10)level was higher than that in the control group,the differences were statistically significant(P<0.05).Conclusion:The combination of Etamsylate Injection and Hemocoagulase and Vitamin K_(1) is highly feasible in the treatment of neonatal hematochezia,which can improve the inflammation,improve the treatment effect and safety.

关 键 词：新生儿便血 酚磺乙胺注射液 白眉蛇毒血凝酶 维生素 K_(1) 

分 类 号：R722.1[医药卫生—儿科]