Ⅰ期心脏康复方案对重症心脏瓣膜病行瓣膜置换术患者疗效及心功能恢复的影响  

Effect of PhaseⅠCardiac Rehabilitation Program on Efficacy and Cardiac Function Recovery of Patients with Severe Valvular Heart Disease Undergoing Valve Replacement

作　　者：向立民 杨榕 姚玲 杨菲 蒋振钦 吴丹 XIANG Limin;YANG Rong;YAO Ling;YANG Fei;JIANG Zhenqin;WU Dan(The Second Affiliated Hospital of Guizhou Medical University,Kaili 556000,China;不详)

机构地区：[1]贵州医科大学第二附属医院,贵州凯里556000

出　　处：《中外医学研究》2024年第22期167-170,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨研究Ⅰ期心脏康复方案对重症心脏瓣膜病(VHD)行瓣膜置换术后患者疗效及心功能恢复的影响。方法:选取2021年1月—2023年5月贵州医科大学第二附属医院收治的70例重症VHD患者作为研究对象,均进行瓣膜置换术,根据术后治疗方法差异性将患者分为对照组和观察组,各35例。对照组术后给予常规干预,观察组在对照组基础上给予Ⅰ期心脏康复,比较两组心功能指标、生物标志物及术后6个月不良心血管事件。结果:观察组出院时左室射血分数(LVEF)高于对照组,左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)低于对照组,差异有统计学意义(P<0.05);观察组出院时B型脑钠肽(BNP)、肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)水平低于对照组,差异有统计学意义(P<0.05);观察组术后6个月不良心血管事件发生率低于对照组,差异有统计学意义(P<0.05)。结论:重症VHD行瓣膜置换术后患者应用Ⅰ期心脏康复方案效果显著,可有效改善心功能指标、生物标志物,降低不良心血管事件发生率。Objective:To investigate the effect of phaseⅠcardiac rehabilitation program on the efficacy and cardiac function recovery of patients with severe valvular heart disease(VHD)undergoing valve replacement.Method:A total of 70 patients with severe VHD who admitted to the Second Affiliated Hospital of Guizhou Medical University from January 2021 to May 2023 were selected as the research objects,all patients were underwent valve replacement,the patients were divided into the control group and the observation group according to the difference of postoperative treatment methods,with 35 cases in each group.The control group was given routine intervention after operation,and the observation group was given phaseⅠcardiac rehabilitation program on the basis of the control group.The cardiac function indexes,biomarkers and adverse cardiovascular events at 6 months after operation were compared between two groups.Result:The left ventricular ejection fraction(LVEF)of the observation group at discharge was higher than that of the control group,and the left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)were lower than those of the control group,the differences were statistically significant(P<0.05);the levels of B-type brain natriuretic peptide(BNP),troponin I(cTnI)and creatine kinase isoenzyme(CK-MB)in the observation group at discharge were lower than those in the control group,and the differences were statistically significant(P<0.05);the incidence of adverse cardiovascular events in the observation group at 6 months after operation was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:The application of phaseⅠcardiac rehabilitation program in patients with severe VHD is remarkable,which can effectively improve cardiac function indexes,biomarkers,and reduce the risk of adverse cardiovascular events.

关 键 词：Ⅰ期心脏康复方案 重症心脏瓣膜病 瓣膜置换术 心功能恢复 

分 类 号：R654.2[医药卫生—外科学]