血红蛋白、白蛋白水平及红细胞分布宽度与心力衰竭预后的相关性研究  

Correlation study of hemoglobin and albumin levels and red blood cell distribution width with prognosis of heart failure

作　　者：卢超[1] 刘俊晓[1] LU Chao;LIU Junxiao(Department of Laboratory,Luoyang Central Hospital,Luoyang 471000,Henan,China)

机构地区：[1]洛阳市中心医院检验科,河南洛阳471000

出　　处：《延边大学医学学报》2024年第2期140-143,共4页Journal of Medical Science Yanbian University

摘　　要：[目的]探讨血红蛋白和白蛋白水平及红细胞分布宽度(RDW)与心力衰竭预后的相关性.[方法]收集自2020年1月至2023年6月间洛阳市中心医院收治的86例心力衰竭患者的临床资料列入观察组,另收集同时期49例非心力衰竭者临床资料列入对照组;比较两组一般资料及血红蛋白、白蛋白水平及RDW.将观察组患者中在出院后3个月内出现全因死亡/心力衰竭再入院的23例纳入预后不良组,其余63例纳入预后良好组;比较两组血红蛋白、白蛋白水平及RDW.进一步分析血红蛋白、白蛋白水平及RDW与心力衰竭预后的相关性及对心力衰竭预后不良的预测价值.[结果]两组患者年龄、性别、体质量指数、是否患有高血压、糖尿病、高血脂间差异均无统计学意义(P>0.05).与对照组比较,观察组血红蛋白、白蛋白水平均明显降低,RDW明显升高,差异均具有统计学意义(P<0.05).与预后不良组比较,预后良好组血红蛋白、白蛋白水平均明显升高,RDW明显降低,差异均具有统计学意义(P<0.05).血红蛋白、白蛋白及RDW的预测阈值分别为131.35、38.22 g/L及0.155 g/dL,三者单一指标及联合预测心力衰竭预后不良的曲线下面积分别为0.627、0.717、0.702及0.809,三者联合预测的曲线下面积最大,灵敏度、特异度亦较高.[结论]血红蛋白、白蛋白水平的明显降低及RDW的明显升高与心力衰竭预后不良有关系,三者联合检查对心力衰竭预后不良的预测有一定的应用价值.OBJECTIVE To investigate the correlation of hemoglobin and albumin levels and red blood cell distribution width(RDW)with the prognosis of heart failure.METHODS The clinical data of 86 patients with heart failure admitted to Luoyang Central Hospital from January 2020 to June 2023 were included in the observation group,and the clinical data of 49 patients without heart failure were included in the control group during the same period.General data,hemoglobin and albumin levels and RDW were compared between the two groups.In the observation group,23 patients who experienced all-cause death/heart failure re-admission within 3 months after discharge were included in the poor prognosis group,and the remaining 63 patients were included in the good prognosis group.The levels of hemoglobin and albumin and RDW were compared between the two groups.The correlation of hemoglobin and albumin levels and RDW with the prognosis of heart failure and the predictive value of poor prognosis of heart failure were further analyzed.RESULTS There were no significant differences in age,gender,body mass index,hypertension,diabetes and hyperlipidemia between the two groups(P>0.05).Compared with the control group,the levels of hemoglobin and albumin in the observation group were significantly decreased,and RDW was significantly increased with statistical significance(P<0.05).Compared with the poor prognosis group,the levels of hemoglobin and albumin in the good prognosis group were significantly increased,and RDW was significantly decreased,the differences were statistically significant(P<0.05).The prediction thresholds of hemoglobin,albumin and RDW were 131.35,38.22 g/L and 0.155 g/dL,respectively.The area under the curve of the three single indicators and the combined prediction of poor prognosis of heart failure were 0.627,0.717,0.702 and 0.809,respectively.The area under the curve of the three combined indicators was the largest,and the sensitivity and specificity were relatively high.CONCLUSION The significant decrease of hemoglobin and

关 键 词：心力衰竭 血红蛋白 白蛋白 红细胞分布宽度 预后 

分 类 号：R541.6[医药卫生—心血管疾病]