^(18)F-FDGPET/CT在肝脏良恶性肿瘤鉴别诊断中的应用价值  

Application Value of ^(18)F-FDG PET/CT in the Differential Diagnosis of Benign and Malignant Liver Tumors

作　　者：罗晓东 董军强[2] LUO Xiaodong;DONG Junqiang(Department of Nuclear Medicine,He'nan Tianyou Tumor Hospital of Integrated Traditional Chinese and Western Medicine,Zhengzhou 451162,China;Department of Nuclear Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]河南天佑中西医结合肿瘤医院核医学科,河南郑州451162 [2]郑州大学第一附属医院核医学科,河南郑州450052

出　　处：《临床医学工程》2024年第8期897-898,共2页Clinical Medicine & Engineering

基　　金：河南省医学科技攻关计划省部共建项目(SBGJ202002064)。

摘　　要：目的探讨^(18)F-FDGPET/CT在肝脏良恶性肿瘤鉴别诊断中的应用价值。方法90例肝脏占位患者根据病理检查结果分为良性组(53例)和恶性组(37例),比较良性组、恶性组的SUV_(max)值,比较恶性组中不同分化程度患者的SUV_(max)值,分析^(18)F-FDGPET/CT对肝脏良恶性肿瘤的鉴别诊断效能。结果恶性组的SUV_(max)值显著高于良性组(P<0.05)。恶性组中不同分化程度患者的SUV_(max)值比较:低分化>中分化>高分化,差异均有统计学意义(P<0.05)。^(18)F-FDGPET/CT诊断肝脏肿瘤的AUC为0.813,95%置信区间为0.738~0.896,敏感度为83.02%,特异度为86.49%。结论^(18)F-FDGPET/CT在肝脏良恶性肿瘤的鉴别诊断中具有较高的敏感度、特异度,有助于临床尽早进行定性诊断。Objective To explore the application value of ^(18)F-FDG PET/CT in the differential diagnosis of benign and malignant liver tumors.Methods According to the results of pathological examination,90 patients with liver space-occupying lesions were divided into the benign group(n=53)and the malignant group(n=37).The SUV_(max) values of the benign group and the malignant group,and the SUVmax values of patients with different degrees of differentiation in the malignant group were compared.The differential diagnostic efficacy of ^(18)F-FDG PET/CT for benign and malignant liver tumors was analyzed.Results The SUV_(max) value of the malignant group was significantly higher than that of the benign group(P<0.05).The SUV_(max) values of patients with different degrees of differentiation in the malignant group from high to low were low differentiation,moderate differentiation and high differentiation,with statistically significant differences(P<0.05).The AUC of ^(18)F-FDG PET/CT in the diagnosis of liver tumors was 0.813,the 95%confidence interval was 0.738~0.896,the sensitivity was 83.02%,and the specificity was 86.49%.Conclusions ^(18)F-FDG PET/CT has high sensitivity and specificity in the differential diagnosis of benign and malignant liver tumors,which is helpful for early clinical qualitative diagnosis.

关 键 词：^(18)F-FDGPET/CT 肝脏肿瘤 鉴别诊断 SUV_(max)值 

分 类 号：R445[医药卫生—影像医学与核医学]