改良序贯疗法与传统三联疗法治疗幽门螺旋杆菌感染患者的效果与安全性比较  

Comparison on the Effects and Safety Between Modified Sequential Therapy and Traditional Triple Therapy in the Treatment of Patients with Helicobacter Pylori Infection

作　　者：钟晨 胡欣 ZHONG Chen;HU Xin(Department of Gastroenterology,Nanfeng County People's Hospital,Fuzhou 344500,China)

机构地区：[1]江西省抚州市南丰县人民医院消化内科,江西抚州344500

出　　处：《临床医学工程》2024年第8期939-940,共2页Clinical Medicine & Engineering

摘　　要：目的比较改良序贯疗法与传统三联疗法治疗幽门螺旋杆菌(Hp)感染的效果与安全性。方法60例Hp感染患者随机分为两组,传统组采用传统三联疗法治疗,改良序贯组采用改良序贯疗法治疗,比较两组的疗效、Hp根除率、不良反应。结果改良序贯组的治疗总有效率、Hp根除率均明显高于传统组,不良反应总发生率明显低于传统组(P<0.05)。结论与传统三联疗法相比,改良序贯疗法治疗Hp感染患者的效果更佳且安全性更高。Objective To compare the effects and safety between modified sequential therapy and traditional triple therapy in the treatment of patients with Helicobacter pylori(Hp)infection.Methods 60 patients with Hp infection were randomly divided into two groups.The traditional group was treated with traditional triple therapy,and the modified sequential group was treated with modified sequential therapy.The efficacy,Hp eradication rate and adverse reactions were compared between the two groups.Results The total effective rate of treatment and Hp eradication rate of the modificd scquential group were significantly higher than those of the traditional group,and the total incidence of adverse reactions was significantly lower than that of the traditional group(P<0.05).Conclusions Compared with traditional triple therapy,modified sequential therapy is more effective and safer in the treatment of patients with Hp infection.

关 键 词：幽门螺旋杆菌感染 改良序贯法 传统三联疗法 疗效 安全性 

分 类 号：R378.2[医药卫生—病原生物学]