丙泊酚复合瑞芬太尼靶控输注麻醉对急性阑尾炎患者行腹腔镜阑尾切除术中血压及心率的影响  

Effect of Propofol Combined with Remifentanil Target-controlled Infusion Anesthesia on Blood Pressure and Heart Rate in Patients with Acute Appendicitis Undergoing Laparoscopic Appendectomy

作　　者：许建文 XU Jian-wen(Department of Anesthesiology,Yongxin County People's Hospital,Yongxin 343400,Jiangxi,China)

机构地区：[1]永新县人民医院麻醉科,江西永新343400

出　　处：《医学信息》2024年第16期92-95,共4页Journal of Medical Information

摘　　要：目的研究丙泊酚复合瑞芬太尼靶控输注麻醉对急性阑尾炎患者行腹腔镜阑尾切除术中血压及心率的影响。方法选取2021年1月-2023年5月我院行腹腔镜阑尾切除术的66例急性阑尾炎患者为研究对象,采用随机数字表法分为对照组和观察组,各组33例。对照组采用丙泊酚复合瑞芬太尼静脉麻醉,观察组采用丙泊酚复合瑞芬太尼靶控输注麻醉,比较两组麻醉指标(麻醉起效时间、自主呼吸时间、清醒时间)、平均血压(MAP)、心率(HR)、疼痛评分(VAS)、镇静评分(Ramsay)、不良反应发生率。结果观察组麻醉起效时间、自主呼吸时间、清醒时间均短于对照组(P<0.05);两组气腹后MAP、HR均低于麻醉诱导前,但观察组均高于对照组(P<0.05);两组拔管时MAP、HR均高于气腹后,但观察组低于对照组(P<0.05);观察组术后8 h的VAS评分低于对照组(P<0.05);观察组拔管时、拔管10 min后Ramsay评分均低于对照组(P<0.05);观察组不良反应发生率为6.06%,低于对照组的15.15%(P<0.05)。结论丙泊酚复合瑞芬太尼靶控输注麻醉在急性阑尾炎患者行腹腔镜阑尾切除术中应用效果良好,可减小对患者血压及心率的影响,提高镇静评分,减轻患者疼痛度,缩短麻醉恢复和起效时间,降低不良反应发生率。Objective To study the effect of propofol combined with remifentanil target-controlled infusion anesthesia on blood pressure and heart rate during laparoscopic appendectomy in patients with acute appendicitis.Methods A total of 66 patients with acute appendicitis who underwent laparoscopic appendectomy in our hospital from January 2021 to May 2023 were selected as the research objects.They were divided into control group and observation group by random number table method,with 33 patients in each group.The control group was treated with propofol combined with remifentanil intravenous anesthesia,and the observation group was treated with propofol combined with remifentanil target-controlled infusion anesthesia.The anesthesia indexes(onset time of anesthesia,spontaneous breathing time,awake time),mean blood pressure(MAP),heart rate(HR),pain score(VAS),sedation score(Ramsay)and incidence of adverse reactions were compared between the two groups.Results The onset time of anesthesia,spontaneous breathing time and awake time in the observation group were shorter than those in the control group(P<0.05).The MAP and HR of the two groups after pneumoperitoneum were lower than those before anesthesia induction,but those of the observation group were higher than those of the control group(P<0.05).The MAP and HR of the two groups at extubation were higher than those after pneumoperitoneum,but those of the observation group were lower than those of the control group(P<0.05).The VAS score of the observation group at 8 h after operation was lower than that of the control group(P<0.05).The Ramsay score of the observation group at extubation and 10 min after extubation was lower than that of the control group(P<0.05).The incidence of adverse reactions in the observation group was 6.06%,which was lower than 15.15%in the control group(P<0.05).Conclusion Propofol combined with remifentanil target-controlled infusion anesthesia is effective in laparoscopic appendectomy in patients with acute appendicitis,which can reduce the effect on

关 键 词：丙泊酚 瑞芬太尼 急性阑尾炎 腹腔镜阑尾切除术 血压 

分 类 号：R971.2[医药卫生—药品]