腹针治疗过敏性鼻炎的随机对照临床试验  

Abdominal acupuncture for treatment of allergic rhinitis:A randomized controlled clinical trial

作　　者：李兆鑫 刘乾 张荣媛 任雪飞 屠建锋 吴家萍 王冬梅 郭彩凤 LI Zhaoxin;LIU Qian;ZHANG Rongyuan;REN Xuefei;TU Jianfeng;WU Jiaping;WANG Dongmei;GUO Caifeng(Department of Acupuncture and Moxibustion,Fangshan Hospital,Beijing University of Chinese Medicine,Beijing 102400,China;Department of Otolaryngology,Fangshan Hospital,Beijing University of Chinese Medicine,Beijing 102400,China;School of Acupuncture-Moxibustion and Tuina,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学房山医院针灸科,北京102400 [2]北京中医药大学房山医院耳鼻喉科,北京102400 [3]北京中医药大学针灸推拿学院,北京100029

出　　处：《中国现代医生》2024年第22期37-40,49,共5页China Modern Doctor

基　　金：北京中医药大学新教师启动基金项目(2022-BUCMXJKY033)。

摘　　要：目的观察腹针治疗过敏性鼻炎(allergic rhinitis,AR)的效果。方法选取2022年8月至10月在北京中医药大学房山医院就诊的27例AR患者,根据随机数字表法将其分为治疗组(15例)和对照组(12例)。治疗组患者采用腹针治疗,对照组患者采用一次性无菌针灸套管模拟进针,无针体刺入穴位。两组均每周治疗3次,共治疗4周。比较两组患者治疗前后的视觉模拟评分法(visual analogue scale,VAS)、鼻结膜炎生活质量问卷(rhinoconjunctivitis quality of life questionnaire,RQLQ)、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)评分及组胺(histamine,HIS)、白三烯D4(leukotriene D4,LTD4)、免疫球蛋白E(immunoglobulin E,IgE)水平。结果治疗后各时间节点,治疗组患者的VAS、RQLQ、PSQI评分及HIS、LTD4、IgE水平均显著低于治疗前(P<0.05)。治疗2周后,两组患者的VAS、RQLQ、PSQI评分及HIS、LTD4、IgE水平比较差异均无统计学意义(P>0.05);治疗4周后及随访4周后,治疗组患者的VAS、RQLQ、PSQI评分及HIS、LTD4水平均显著低于对照组(P<0.05)。结论腹针治疗AR具有良好的治疗效果,可显著提高患者的生存质量,降低HIS、LTD4、IgE水平,值得临床推广。Objective To observe the effect of abdominal acupuncture in treating allergic rhinitis(AR).Methods Twenty-seven AR patients who attended Fangshan Hospital,Beijing University of Chinese Medicine from August to October 2022 were selected.They were divided into treatment group(15 cases)and control group(12 cases)according to randomized numerical table method.The treatment group received abdominal acupuncture.The control group at the same point was used one-time sterile cannula acupuncture to simulate acupuncture,but no needle was inserted into the acupoint.Two groups were treated,3 times a week for 4 weeks.The visual analogue scale(VAS),rhinoconjunctivitis quality of life questionnaire(RQLQ),Pittsburgh sleep quality index(PSQI)scores,and the histamine(HIS),leukotriene D4(LTD4),immunoglobulin E(IgE)levels were compared between two groups before and after treatment.Results At each time point after treatment,the VAS,RQLQ,PSQI scores and HIS,LTD4,IgE levels of patients in treatment group were significantly lower than those before treatment(P<0.05).There were no statistically significant differences in VAS,RQLQ,and PSQI scores,the HIS,LTD4,and IgE levels after 2-week treatment in both groups(P>0.05).After 4-week treatment and follow-up 4-week,the VAS,RQLQ,and PSQI scores,the HIS,and LTD4 levels in treatment group were significantly lower than those in control group(P<0.05).Conclusion Abdominal acupuncture has good therapeutic effect on AR and significantly improves life quality of the patients,which can reduce the levels of HIS,LTD4 and IgE.The therapy is worthy of clinical application.

关 键 词：腹针 过敏性鼻炎 鼻结膜炎生活质量问卷 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]