中药穴位贴敷联合音乐疗法对宫颈癌化疗所致恶心呕吐的干预效果分析  

Intervention effect of TCM acupoint sticking combined with music therapy on chemotherapy-induced nausea and vomiting in patients with cervical cancer

作　　者：冒小平[1] 邱小丽[1] 陆云[1] 宋红霞 张兰凤 MAO Xiaoping;QIU Xiaoli;LU Yun;SONG Hongxia;ZHANG Lanfeng(Department of Gynecologic Oncology,Nantong Tumor Hospital,Nantong,Jiangsu 226361;Rugao Boai Hospital,Rugao,Jiangsu 226599)

机构地区：[1]江苏省南通市肿瘤医院妇瘤科,江苏南通226361 [2]江苏省如皋博爱医院,江苏如皋226599

出　　处：《河北中医》2024年第8期1328-1332,共5页Hebei Journal of Traditional Chinese Medicine

基　　金：2023年度南通市卫生健康委科研课题(编号:MSZ2023043)。

摘　　要：目的观察中药穴位贴敷联合音乐疗法对宫颈癌化疗所致恶心呕吐的干预效果。方法纳入宫颈癌化疗治疗所致恶心呕吐的患者76例,采用随机数字表法分为2组。对照组37例予音乐疗法,研究组39例予中药穴位贴敷联合音乐疗法干预。2组均21天为1个疗程,治疗4个疗程。比较2组治疗前后血小板计数、白细胞计数、血红蛋白水平、恶心及呕吐指数评估量表(INVR)和生活质量评分(QOL),记录2组恶心呕吐发生情况,统计对比2组疗效。结果研究组总有效率92.31%(36/39),对照组总有效率72.97%(27/37),研究组临床疗效优于对照组(P<0.05)。2组治疗后血小板计数、白细胞计数及血红蛋白水平均较本组治疗前降低(P<0.05),且研究组治疗后均低于对照组(P<0.05)。2组治疗前后INVR评分比较2组治疗后INVR各项评分均较本组治疗前降低(P<0.05),且研究组治疗后均低于对照组(P<0.05)。2组治疗后QOL各项评分均较本组治疗前升高(P<0.05),且研究组治疗后均高于对照组(P<0.05)。2组治疗当日恶心呕吐发生情况比较差异无统计学意义(P>0.05)。治疗结束后当日研究组恶心呕吐发生率均低于对照组(P<0.05)。结论经中药穴位贴敷联合音乐疗法对宫颈癌化疗所致恶心呕吐患者进行治疗,能显著改善患者恶心呕吐症状,提高患者生活质量,临床效果显著。Objective To observe the intervention effect of traditional Chinese medicine(TCM)acupoint sticking combined with music therapy on chemotherapy-induced nausea and vomiting in patients with cervical cancer(CC).Methods A total of 76 CC patients with chemotherapy-induced nausea and vomiting were randomly selected to receive either music therapy(control group,n=37)or TCM acupoint sticking plus music therapy(study group,n=39)for 4 courses(1 course for 21 days).The platelet count(PC),white blood cell(WBC)count,hemoglobin(Hb)level,the Index of Nausea,Vomiting and Retching(INVR),Quality of life(QOL),incidences of nausea and vomiting were included as comparisons before and after the intervention.The curative effect was assessed.Results The overall effective rate in the study group was better than that in the control group(92.31%[36/39]vs 72.97%[27/37],P<0.05).After the intervention,PC,WBC count,Hb level in the both groups were significantly decreased(P<0.05),the decreases were more notably in the study group compared with the control group(P<0.05).Moreover,INVR scores were significantly decreased in the both groups(P<0.05),but QOL scores were significantly increased(P<0.05),and the study group was superior to the control group for INVR and QOL scores(all P<0.05).None of the incidences of nausea and vomiting differed significantly between groups during the intervention(P>0.05).Whereas,which were significantly lower in the study group than in the control group at the end of the intervention(P<0.05).Conclusion TCM acupoint sticking combined with music therapy has significant clinical effects on chemotherapy-induced nausea and vomiting in CC patients,which can significantly improve the symptoms of nausea and vomiting,and the quality of life.

关 键 词：宫颈肿瘤 化疗 恶心呕吐 穴位贴敷 音乐疗法 

分 类 号：R711.74[医药卫生—妇产科学] R245.9[医药卫生—临床医学]