醋酸洗必泰/氧化石墨烯复合物的抗菌性能研究  

Antibacterial Property of Chlorhexidine Acetate/Graphene Oxide Composite

作　　者：张劲林[1] 刘惠娣 ZHANG Jinglin;LIU Huidi(Guangdong Polytechnic,Foshan 528041,China)

机构地区：[1]广东职业技术学院,广东佛山528041

出　　处：《河南科技》2024年第14期76-79,共4页Henan Science and Technology

基　　金：佛山市自筹经费类科技创新项目(2320001006258);广东职业技术学院校级科研项目(XJKY202331)。

摘　　要：【目的】研究醋酸洗必泰/氧化石墨烯复合物的抗菌性能。【方法】采用Brodie法所制备得到氧化石墨烯,使用插层改性的方法合成醋酸洗必泰/氧化石墨烯复合物。运用XRD和FTIR表征复合物的结构,同时借助体外抗菌试验评价复合物的抗菌性能。【结果】与氧化石墨烯对大肠杆菌和金黄色葡萄球菌的抗菌率相比,复合物对大肠杆菌和金黄色葡萄球菌的抗菌率分别提高了约11.5倍和7.7倍。【结论】醋酸洗必泰的引入可大幅度提高氧化石墨烯的抗菌活性。[Purposes]This paper aimed to investigate the antibacterial property of chlorhexidine acetate/graphene oxide composite.[Methods]Graphene oxide was prepared using Brodie method.Subsequently,chlorhexidine acetate/graphene oxide composite was synthesized by intercalation modification method.The structure of the composite was characterized using XRD and FTIR,and the antibacterial property of the composite was evaluated through in vitro antibacterial experiment.[Findings]Compared with the an-tibacterial rate of graphene oxide against escherichia coli and Staphylococcus aureus,the antibacterial rate of the composite against escherichia coli and Staphylococcus aureus increased by ca.11.5 and 7.7 times,respectively.[Conclusions]The introduction of chlorhexidine acetate could significantly improve the antibacterial activity of graphene oxide.

关 键 词：氧化石墨烯 醋酸洗必泰 复合物 抗菌性能 

分 类 号：TB33[一般工业技术—材料科学与工程]