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作 者:方芳 王理槐[1] 王贤文[1] 覃芳媛 孟琼 肖安琴 彭廷云[1] FANG Fang;WANG Lihuai;WANG Xianwen;QIN Fangyua;MENG Qiong;XIAO Anqin;PENG Tingyun(The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,China)
机构地区:[1]湖南中医药大学第一附属医院,湖南长沙410007
出 处:《中国中医药信息杂志》2024年第9期73-78,共6页Chinese Journal of Information on Traditional Chinese Medicine
基 金:国家自然科学基金(81973914);湖南省自然科学基金(2021JJ30525);2021年湖南省临床医学研究中心(2021SK4023)。
摘 要:目的 了解白花蛇舌草研究热点及发展趋势,为相关临床研究提供参考。方法 检索中国知识资源总库(CNKI)、中国学术期刊数据库(万方数据)、中文科技期刊数据库(VIP)、中国生物医学文献数据库(CBM)2003年1月1日-2023年9月5日收录的白花蛇舌草研究文献。使用NoteExpress3.7软件管理文献题录,利用CiteSpace6.2.R2软件对作者、机构及关键词进行可视化分析。结果 纳入2 713篇文献,年发文量呈波动上升趋势;来源期刊617种,其中《陕西中医》发文最多(136篇);涉及799位作者,核心作者包括刘健、林久茂、彭军等;主要研究机构有南京中医药大学、山东中医药大学、广州中医药大学等;近年高频关键词有名医经验、数据挖掘、用药规律、细胞凋亡、肺癌、肝癌等;研究前沿涉及作用机制、数据挖掘及分子对接等。结论 白花蛇舌草研究热点主要集中在疾病治疗、配伍应用、成分分析、作用机制,以及各医家临床应用白花蛇舌草的经验总结等方面。数据挖掘名医用药规律、通过网络药理学及分子对接技术预测潜在药物靶点并探讨其作用机制为该领域研究趋势。Objective To understand the research hotspots and development trend of Hedyotidis Herba;To provide reference for related clinical studies.Methods The literature on Hedyotidis Herba was retrieved from CNKI,Wanfang Data,VIP and CBM from January 1,2003 to September 5,2023.NoteExpress 3.7 software was used to manage the bibliothems,and CiteSpace 6.2.R2 software was used to visualize the authors,institutions and keywords.Results Totally 2713 articles were included,and the annual number of publications showed a fluctuating upward trend.There were 617 source journals,among which Shaanxi Journal of Traditional Chinese Medicine published the most articles(136).799 authors were involved,and the core authors included Liu Jian,Lin Jiumao,Peng Jun,etc.The main research institutions were Nanjing University of Chinese Medicine,Shandong University of Traditional Chinese Medicine,Guangzhou University of Chinese Medicine and so on.In recent years,high-frequency keywords were experience of famous doctors,data mining,medication law,apoptosis,lung cancer,liver cancer,etc.The research frontier involved the mechanism,data mining and molecular docking.Conclusion The study of the Hedyotidis Herba mainly focuses on disease treatment,compatibility application,component analysis,mechanism,and the experience summary of clinical application of the Hedyotidis Herba.Data mining for medication law of famous doctors,prediction of potential drug targets through network pharmacology and molecular docking technology and exploration of their mechanisms are the research trends in this field.
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