水灌肠超声联合剪切波弹性成像对结肠良恶性肿物的诊断价值  

Diagnostic value of hydrocolonic sonography combined with shear-wave elastography for benign and malignant tumors of colon

作　　者：郑若婷 翟玉霞[1] 邱仲贤 陈哲[1] Zheng Ruoting;Zhai Yuxia;Qiu Zhongxian;Chen Zhe(Department of Ultrasound,The Second Affiliated Hospital of Shantou University Medical College,Shantou 515000,China)

机构地区：[1]汕头大学医学院第二附属医院超声科,汕头515000

出　　处：《中国医学装备》2024年第8期54-59,共6页China Medical Equipment

基　　金：2022年汕头市科技计划医疗卫生项目(汕府科〔2022〕81号-39)。

摘　　要：目的:探讨水灌肠超声联合剪切波弹性成像(SWE)技术在结肠良恶性肿物中的诊断价值。方法:选取2021年2月至2022年8月汕头大学医学院第二附属医院水灌肠超声检查中发现肿物的63例患者,采用SWE技术分别对肿物进行点式剪切波弹性成像(pSWE)及二维剪切波弹性成像(2D-SWE),获取剪切波速度(SWV),根据病理结果将其分为良性组(20例)和恶性组(43例),绘制受试者工作特征(ROC)曲线,预测结肠恶性病变SWV的临界值,比较2D-SWE杨氏模量平均值(E_(mean))、最小值(E_(min))及最大值(E_(max))。结果:恶性组SWV值明显高于良性组,由ROC曲线可知,在2D-SWE,当SWV截断值分别为1.945 m/s、1.485 m/s和2.445 m/s,E_(mean)、E_(min)及E_(max)的ROC曲线下面积(AUC)最大,其中E_(max)的灵敏度和特异度最佳,分别为95.3%和95%;而pSWE只存在平均值,当SWV截值为1.885 m/s,AUC最大。两组2D-SWE的E_(mean)与pSWE均具有相关性,良恶性组的相关系数分别为0.725、0.803。结论:水灌肠超声联合SWE的客观量化指标,对鉴别肠道良恶性病变有较高的参考价值,且无创、依从性好,值得临床应用。Objective:To investigate the diagnostic value of hydrocolonic sonography combined with shear-wave elastography(SWE)for benign and malignant tumors of colon.Methods:A total of sixty-three patients with tumor,who were confirmed by hydrocolonic sonography in the Second Affiliated Hospital of Shantou University Medical College from February 2021 to August 2022,were selected.The point-type SWE(pSWE)and two-dimensional SWE(2D-SWE)were performed on the tumors by SWE technique,respectively,to obtain shear wave velocity(SWV).And then,they were divided into benign group(N=20)and malignant group(N=43)according to pathological results.Receiver operating characteristic(ROC)curve was constructed to predict the SWV critical value of malignantly colonic lesions.In addition,the mean(E_(mean)),the minimum value(E_(min))and the maximum value(E_(max))of Young’s modulus between two groups were compared.Results:The SWV value of malignant group was significantly higher than that of benign group.The results of ROC curve of 2D-SWE indicated that the values of area under curve(AUC)of E_(mean),E_(min)and Emax were maximum when the SWV cutoff values were respectively 1.945 m/s,1.485 m/s and 2.445 m/s.Among of them,the sensitivity and specificity of E_(max)were the best,which were respectively 95.3%and 95%.However,the pSWE only had mean,which AUC was the biggest when SWV cutoff value was 1.885 m/s.There were correlations in both two groups between E_(mean)and pSWE,and the correlation coefficients of benign and malignant groups were respectively 0.725 and 0.803.Conclusion:Hydrocolonic sonography combined with SWE technique is an objective and quantitative index,which has higher reference value for differentiating benign and malignant intestinal lesions.It is non-invasive and it has good compliance,which is worthy in clinical application.

关 键 词：水灌肠超声 剪切波弹性成像(SWE) 结肠良恶性病变 

分 类 号：R445.1[医药卫生—影像医学与核医学]