阴道分泌物分离出葡萄牙假丝酵母菌一株报告  

One strain of Candida lusitaniae isolated from vaginal secretions:a case report

作　　者：刘慧 卢发强 LIU Hui;LU Faqiang(Department of Laboratory,Zhongshan Hospital Affiliated to Dalian University,Dalian 116001,China;Department of Laboratory,Tongren People's Hospital,Tongren 554300,China)

机构地区：[1]大连大学附属中山医院检验科,大连116001 [2]铜仁市人民医院检验科,铜仁554300

出　　处：《诊断学理论与实践》2024年第3期330-334,共5页Journal of Diagnostics Concepts & Practice

摘　　要：葡萄牙假丝酵母菌性阴道炎在临床较为罕见,本文报道1例由葡萄牙假丝酵母菌(Candida lusitaniae,CL)引起外阴阴道假丝酵母菌病(vulvovaginal candidiasis,VVC)的患者。本例患者为40岁女性,主要临床表现为月经前外阴瘙痒、白带增多、反复半年。将患者阴道分泌物直接涂片分别进行免疫荧光染色、革兰染色、瑞氏染色,镜检找到真菌孢子,CHROMagar显色平板鉴定为光滑假丝酵母菌,梅里埃VITEK-2 Compact全自动微生物分析系统鉴定为CL。该病例的诊治过程提示,CL实验室诊断易与其他假丝酵母菌混淆,为防止漏报或错报,对于难治病例需要考虑少见菌株感染可能。Candida lusitaniae vaginitis is clinically rare.This article reports a case of vaginitis caused by Candida lusitaniae in a 40-year-old female patient.The main clinical manifestations of the patient were pruritus vulvae before menstruation,increased vaginal discharge,and recurrent symptoms for six months.Vaginal secretions from the patient were directly smeared and subjected to immunofluorescence staining,Gram staining,and Giemsa staining,revealing fungal spores upon microscopic examination.Identification using CHROMagar chromogenic plates revealed the presence of Candida lusitaniae.The bioMérieux VITEK-2 Compact automated microbiology system identified the organism as Candida lusitaniae.The diagnostic and treatment process of this case suggests that laboratory diagnosis of Candida lusitaniae can easily be confused with other Candida species.To prevent underreporting or misreporting,it is necessary to consider the possibility of infection by rare strains in refractory cases.

关 键 词：菌种鉴定 葡萄牙假丝酵母菌 非白假丝酵母菌 科玛嘉显色培养基 免疫荧光染色 

分 类 号：R446.1[医药卫生—诊断学] R711.73[医药卫生—临床医学]