Neuroform Atlas支架与Enterprise支架辅助弹簧圈栓塞治疗颅内宽颈动脉瘤的效果比较  

Comparison of Neuroform Atlas stent and Enterprise stent assisted spring coil embolization in the treatment of intracranial wide-necked aneurysms

作　　者：马学雷 耿守科 MA Xue-lei;GENG Shou-ke(Second Department of Neurology,Pingdu Third People's Hospital,Qingdao 266700,China)

机构地区：[1]平度市第三人民医院外二科,266700

出　　处：《中国实用医药》2024年第15期1-5,共5页China Practical Medicine

摘　　要：目的探讨Neuroform Atlas支架与Enterprise支架辅助弹簧圈栓塞治疗颅内宽颈动脉瘤(IWA)的效果。方法选取IWA患者72例,采用随机数字表法分为A、B组,每组36例。A组采用Neuroform Atlas支架辅助弹簧圈栓塞治疗,B组采用Enterprise支架辅助弹簧圈栓塞治疗。比较两组Raymond分级、脑血流灌注情况、改良Rankin量表(mRS)评分及并发症发生率。结果A组和B组术后即刻Raymond分级Ⅰ级占比分别为75.00%(27/36)、66.67%(24/36),比较差异不显著(P>0.05);两组术后即刻Raymond分级比较,差异不显著(P>0.05);A组术后6个月Raymond分级Ⅰ级占比为83.33%(30/36),高于B组的61.11%(22/36)(P<0.05);A组术后6个月Raymond分级优于B组(P<0.05)。A组和B组术前局部脑血容量(rCBV)、颅内压(ICP)比较,差异不显著(P>0.05);A组和B组术后6个月rCBV均高于术前,ICP均低于术前,且A组术后6个月rCBV(2.18±0.42)ml/100 g高于B组的(1.95±0.33)ml/100 g,ICP(16.24±2.63)mm Hg(1 mm Hg=0.133 kPa)低于B组的(18.52±2.70)mm Hg(P<0.05)。随访6个月,A组mRS评分0~2分占比94.44%高于B组的77.78%(P<0.05)。两组并发症发生率比较,差异不显著(P>0.05)。结论与Enterprise支架相比,Neuroform Atlas支架辅助弹簧圈栓塞治疗IWA的完全闭塞率更高,同时能更好地改善患者脑血流灌注和短期预后,而两种支架的并发症发生率相似。Objective To explore the effect of Neuroform Atlas stent and Enterprise stent assisted spring coil embolization in the treatment of intracranial wide-necked aneurysms(IWA).Methods 72 patients with IWA were selected and randomly divided into group A and group B,with 36 cases in each group.Group A received Neuroform Atlas stent assisted spring coil embolization,while group B received Enterprise stent assisted spring coil embolization.The Raymond grading,cerebral blood perfusion,modified Rankin scale(mRS)score and complication rate were compared between the two groups.Results The percentage of Raymond gradeⅠin group A and group B immediately after surgery were 75.00%(27/36)and 66.67%(24/36),and the difference was not significant in comparison(P>0.05).There was no significant difference in Raymond grading between the two groups(P>0.05).The percentage of Raymond gradeⅠin group A was 83.33%(30/36)at 6 months after surgery,which was higher than 61.11%(22/36)in group B(P<0.05).Raymond grading of group A was better than that of group B at 6 months after surgery(P<0.05).There were no significant differences in regional cerebral blood volume(rCBV)and intracranial pressure(ICP)between group A and group B(P>0.05).At 6 months after surgery,rCBV of group A and group B was higher than that before surgery,ICP was lower than that before surgery;group A had rCBV of(2.18±0.42)ml/100 g,which was higher than(1.95±0.33)ml/100 g of group B;group A had ICP of(16.24±2.63)mm Hg(1 mm Hg=0.133 kPa),which was lower than(18.52±2.70)mm Hg of group B(P<0.05).After 6 months of follow-up,the percentage of mRS scores of 0-2 points in group A was 94.44%,which was higher than 77.78%in group B(P<0.05).There was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Compared with Enterprise stents,Neuroform Atlas stents assisted with spring coil embolization have a higher complete occlusion rate for IWA,and can better improve cerebral blood flow perfusion and short-term prognosis in patients. The i

关 键 词：颅内宽颈动脉瘤 弹簧圈栓塞 Enterprise支架 Neuroform Atlas支架 脑血流灌注 

分 类 号：R651.12[医药卫生—外科学]