局部臭氧联合散瘀消痛散外敷对高位肛瘘术后创面愈合的影响  

Effect of Local Ozone Combined with External Application of Sanyu Xiaotong Powder on Wound Healing after High Anal Fistula Operation

作　　者：王莎莎 刘棚越 李江琳[1] WANG Sha-sha;LIU Peng-yue;LI Jiang-lin(First Affiliated Hospital of Henan University,Kaifeng,Henan 475000)

机构地区：[1]河南大学第一附属医院,河南开封475000

出　　处：《中国肛肠病杂志》2024年第7期45-47,共3页Chinese Journal of Coloproctology

基　　金：2022年河南省医学科技攻关计划项目(编号LHGJ20220649)。

摘　　要：目的:分析局部臭氧联合散瘀消痛散外敷对高位肛瘘术后创面愈合的影响。方法:将我院2020年5月至2022年3月行高位肛瘘切除术86例患者分为对照组41例和观察组45例,术后对照组患者采用局部臭氧治疗,观察组患者采用局部臭氧联合散瘀消痛散外敷治疗,观察2组患者的疗效,比较2组患者术后创面疼痛、渗出液、肿胀评分以及不同时点凋亡分子表达和创面愈合情况。结果:观察组患者总有效率明显高于对照组(P<0.05);术后第7天和第15天,观察组患者的疼痛评分、渗出液评分、肿胀评分以及Bax、caspase-3和P53的表达均明显低于对照组(P<0.05);观察组患者创面愈合时间明显短于对照组(P<0.05)。结论:局部臭氧联合散瘀消痛散外敷用于肛瘘患者术后创面可明显减轻疼痛、水肿,促进创面愈合,疗效显著。Objective To analyze the effect of local ozone combined with external application of Sanyu Xiaotong Powder on wound healing after high anal fistula operation.Methods A total of 86 patients un-dergoing high anal fistulectomy in our hospital from May 2020 to March 2022 were divided into control group(41 cases)and observation group(45 cases).After the operation,patients in the control group were treated with local ozone treatment,while patients in the observation group were treated with local ozone combined with external application of Sanyu Xiaotong Powder.The scores of postoperative wound pain,exudation and swelling,apoptotic molecule expression and wound healing were compared between the two groups.Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).The scores of pain,exudation and swelling,and the expressions of Bax,caspase-3 and P53 in the observation group were significantly lower than those in the control group on the 7th and 15th days after operation(P<0.05).The wound healing time of the observation group was sig-nificantly shorter than that of the control group(P<0.05).Conclusion The application of local ozone combined with external application of Sanyu Xiaotong Powder can significantly reduce pain and swelling,and promote wound healing in patients with anal fistula.

关 键 词：高位肛瘘 手术 局部臭氧 散瘀消痛散 创面愈合 

分 类 号：R657.16[医药卫生—外科学]