肿瘤分化程度对肝内胆管细胞癌超声造影增强特征的影响  

Effect of Tumor Differentiation Degree on Contrast-Enhanced Ultrasound Features of Intrahepatic Cholangiocellular Carcinoma

作　　者：孙波 邓家琦 况容 周静 Sun Bo;Deng Jiaqi;Kuang Rong;Zhou Jing(Department of Ultrasound,Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan 646000,China)

机构地区：[1]西南医科大学附属医院超声科,四川省泸州市646000

出　　处：《中国超声医学杂志》2024年第8期898-901,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 探讨肿瘤分化程度对肝内胆管细胞癌(ICC)超声造影增强特征的影响。方法 回顾性分析经组织病理学确诊的50例ICC患者的临床资料,所有患者术前均行常规超声和超声造影检查。根据术后组织病理学不同的肿瘤分化程度进行分组,并采用卡方检验和t检验来比较组间的差异。结果 本研究共纳入50例患者,依据患者术后的病理分化程度分为3组(低分化组、中分化组、高分化组),其中男性29例(58.0%),平均年龄(56.3±8.8)岁,不同分化程度的病灶在动脉期强化方式及门静脉期强化方式上差异存在统计学意义(P<0.05)。结论 肿瘤分化程度对ICC的超声造影特征有显著影响,对于在动脉期表现为不均匀高强化及门静脉期表现为边缘征的病灶,在排除转移瘤的情况后,应该考虑为ICC。Objective To investigate the influence of the degree of tumor differentiation on the ultrasonographic enhancement features in patients with intrahepatic cholangiocellular carcinoma(ICC).Methods The clinical data of 50 patients with ICC diagnosed by histopathology were retrospectively analyzed,and all of them underwent conventional ultrasound and contrast-enhanced ultrasound before operation.They were grouped according to different degrees of tumor differentiation on postoperative histopathology,and the chi-square test and t-test were used to compare the differences between groups.Results A total of 50 patients were included in this study,and they were divided into three groups(low-differentiation group,middle-differentiation group,and high-differentiation group)based on their postoperative degree of pathologic differentiation,of which 29(58.0%)were male,and the mean age was(56.3±8.8)years old.There was a significant difference among lesions with different degrees of differentiation in the mode of arterial-phase enhancement and the mode of portal-vein-phase enhancement(P<0.05).Conclusions The degree of tumor differentiation has a significant effect on the contrast-enhanced ultrasound features of ICC.Signs of inhomogeneous hyper-intensification in the arterial phase and margin sign in the portal venous phase should be considered as supporting evidence for ICC after exclusion of metastases.

关 键 词：肝内胆管细胞癌 超声造影 分化程度 

分 类 号：R445.1[医药卫生—影像医学与核医学] R735.7[医药卫生—诊断学]