基于电网络理论和计算流体力学的血流仿真  

Blood Flow Simulation Based on Electrical Ne twork Theory and Computational Fluid Dynamics

作　　者：齐天成 张嘉惠[2] 张怀新[1] QI Tian-cheng;ZHANG Jia-hui;ZHANG Huai-xin(School of Naval Architecture,Ocean and Civil Engineering,Shanghai Jiao Tong Univers ity,Shanghai 200240,China;Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China)

机构地区：[1]上海交通大学船舶海洋与建筑工程学院,上海200240 [2]上海交通大学医学院附属仁济医院,上海200127

出　　处：《计算机仿真》2024年第7期394-398,共5页Computer Simulation

基　　金：国家自然科学基金(52171316);上海交通大学“交大之星”计划医工交叉研究基金(YG2019QNA29)。

摘　　要：人体的上肢动脉包括肱动脉和桡动脉,两段动脉也经常被作为测得人体血压及脉搏波的关键部位,反映出了丰富的生理病理信息,对此进行研究对心血管疾病的诊断具有着重要意义。对比结合了基于弹性腔的电网络模型法和双向流固耦合计算流体力学模型法,分别建立了在相同结构和力学参数下的两种仿真模型,通过两种方法在不同尺度下的优势互补,对人体在健康及动脉粥样硬化状态下的上肢动脉段的血流动力学问题进行了研究。一方面通过电网络模型对动脉脉搏波进行了动态仿真,发现在动脉粥样硬化下脉搏波的主波波峰出现了明显的升高和前滞现象,另一方面通过双向流固耦合计算流体力学法分析了血液流场的局部特性,从而为粥样硬化等心血管疾病的形成机理及预测提供参考。The upper extremity arteries of the human body include the brachial artery and the radial artery.These two arteries are often used as the key parts for measuring human blood pressure and pulse wave,reflecting a lot physiological and pathological information.We compare and combine the electrical network model method based on the elastic cavity and the bidirectional fluid-st ructure coupling computational fluid dynami cs model method.To study the hemodynamics of the upper limb arterial segment in the human body in the healthy and ather osclerotic state,two simulation models under the same structural and mechanical parameters are established.On the one hand,the arterial pulse wave is dynamically simulated through the electrical network model,and it is found that the main wave peak of the pulse wave under atherosclerosis has obvious rise and lag.On the other hand,by the the bidirectional fluid-structure coupling computational fluid dynamics method,we analyze the local mechanical proper ties of the blood flow field such as velocity,pressure,so as to provide references for the formation and prediction of atherosclerosis and other cardiovascular diseases.

关 键 词：电网络 计算流体力学 粥样硬化 上肢动脉 

分 类 号：TP391.9[自动化与计算机技术—计算机应用技术]