新型融合BEV/BPV信息的高分辨率快速磁共振成像方法  

A Novel High-resolution Fast Magnetic Resonance Imaging Method Incorporating BEV/BPV Fusion Information

作　　者：陈佳赟 王小奇 覃仕瑞 魏然 陈德启 张可 曹莹 戴建荣 唐源 CHEN Jiayun;WANG Xiaoqi;QIN Shirui;WEI Ran;CHEN Deqi;ZHANG Ke;CAO Ying;DAI Jianrong;TANG yuan(Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China;Feiyan Sihai Medical Technology Co.,Beijing 100800,China)

机构地区：[1]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京100021 [2]飞燕四海医疗科技有限公司,北京100800

出　　处：《原子核物理评论》2024年第1期504-509,共6页Nuclear Physics Review

基　　金：国家自然科学基金资助项目(12105368);中国癌症基金会北京希望马拉松专项基金项目(LC2020A29)。

摘　　要：建立了一种新型融合Beam Eye View(BEV)/Beam Path View(BPV)信息的高分辨率快速磁共振成像方法。选取3例肝转移磁共振引导放疗(MRgRT)患者,采集同一患者使用腹部加压带限制腹部运动(RAM组)的运动管理模式下和自由呼吸(FB组)模式下图像,共计31 200帧。采用邻近肿瘤具有明确边界的血管进行肿瘤位置跟踪,计算其在95%置信区间下的径向矢量运动幅度差异△R95。在BEV/BPV平面上RAM组和FB组在所有分次中的△R95的差异分别为:患者1均小于0.58 mm;患者2高达2.57 mm以上;患者3分别为0.71 mm/1.05 mm。结果表明,腹部压迫方案可以有效地减小肿瘤的运动幅度,另外肿瘤运动幅度△R95变化具有完全的个体相关性。该方法也可作为MRgRT技术中肿瘤放疗外放边界缩小的影像基础。This study establishes a novel high-resolution fast magnetic resonance imaging(MRI)method that incorporates Beam Eye View(BEV)and Beam Path View(BPV)fusion information.Three liver metastasis patients undergoing MRI guided radiotherapy(MRgRT)were selected.A total of 31200 frames of MRI images were acquired from each patient using two motion patterns:restricted abdominal motion using an abdominal compression belt(RAM group)and free breathing(FB group).Tumor tracking was performed using nearby vessels with clear boundaries,and the radial vector motion amplitude difference(∆R95)within the 95%confidence interval was calculated.The differences inΔR95 between the RAM and FB groups in all fractions on the BEV/BPV plane were as follows:for Patient 1,they were all less than 0.58 mm;for Patient 2,they were greater than 2.57 mm;for Patient 3,they were 0.71 and 1.05 mm,respectively.The results indicate that the abdominal compression technique can effectively reduce tumor motion magnitude,and the tumor motion magnitudeΔR95 variation is highly individual-specific.This method can serve as an imaging basis for the tumor margin reduction in MRgRT.

关 键 词：高分辨率快速MRI成像 BEV/BPV信息融合 运动幅度比较 肝转移患者 磁共振引导放疗 

分 类 号：R815.6[医药卫生—放射医学]