胰源性糖尿病的发病机制探析  

Pathogenesis of pancreatogenic diabetes

作　　者：王晨晓[1] 王晓[1] 王希望 金晶晶 王莹 刘江凯[1] 燕树勋[2] WANG Chenxiao;WANG Xiao;WANG Xiwang;JIN Jingjing;WANG Ying;LIU Jiangkai;YAN Shuxun(Department of Hepatology and Spleen-Stomach,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China;Department of Endocrinology,The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第一附属医院脾胃肝胆病科,郑州450000 [2]河南中医药大学第一附属医院内分泌科,郑州450000

出　　处：《临床肝胆病杂志》2024年第8期1715-1720,共6页Journal of Clinical Hepatology

基　　金：国家中医临床研究基地科研专项(2021JDZY034);河南省中医药科学研究专项课题(2022ZY1030)。

摘　　要：胰源性糖尿病是一种继发于胰腺外分泌疾病的糖尿病,2014年被美国糖尿病学会正式命名,慢性胰腺炎和胰腺癌是其最主要的发病原因。该病的发病机制尚不完全明确,系统的治疗方案尚未形成,因此国内外关于胰源性糖尿病的误诊率极高,且研究发现该型糖尿病患者与2型糖尿病相比具有更高的死亡和再入院风险,这无疑对患者的健康和临床治疗充满挑战。因此充分了解、早期正确识别及诊断胰源性糖尿病,对降低该病的致残率与病死率具有重要意义。本文对胰源性糖尿病可能的发病机制进行阐述与分析。Pancreatogenic diabetes is a type of diabetes secondary to pancreatic exocrine disease,and it was officially named by American Diabetes Association in 2014.Chronic pancreatitis and pancreatic cancer are the most common causes of pancreatogenic diabetes.The pathogenesis of this disease remains unclear,and there is still a lack of systematic treatment regimens,which leads to the extremely high misdiagnosis rate of pancreatogenic diabetes in China and globally.In addition,studies have shown that compared with patients with type 2 diabetes,patients with pancreatogenic diabetes tend to have higher risks of death and readmission,which brings great challenges to the health and clinical treatment of patients.Therefore,the comprehensive understanding and early accurate identification and diagnosis of pancreatogenic diabetes are of great significance in reducing the disability and mortality rates of this disease.This article elaborates on the possible pathogenesis of pancreatogenic diabetes.

关 键 词：胰源性糖尿病 病理过程 诊断 

分 类 号：R587.1[医药卫生—内分泌]