磁共振T2WI-FS与ADC技术评估宫颈癌患者淋巴结转移与脉管间隙浸润效果  

Effect of T2-weighted imaging with fat suppression and apparent diffusion coefficient technology for evaluating the situations of lymph node metastasis and lymph vascular space invasion of patients with cervical cancer

作　　者：潘贝贝 韩贺山 李传乐 刘峰 PAN Beibei;HAN Heshan;LI Chuanle;LIU Feng(Fuyang Cancer Hospital,Fuyang,Anhui Province,236000)

机构地区：[1]安徽省阜阳市肿瘤医院,236000

出　　处：《中国计划生育学杂志》2024年第8期1914-1917,1922,共5页Chinese Journal of Family Planning

基　　金：阜阳市卫生健康委员会第一批科研立项项目(FY2021-083)。

摘　　要：目的:观察磁共振T2加权脂肪抑制序列(T2WI-FS)与表观扩散系数(ADC)技术评估宫颈癌(CC)患者淋巴结转移(LNM)与脉管间隙浸润(LVSI)的价值。方法:回顾性分析2018年1月-2023年9月本院收治经手术病理证实的CC患者120例临床资料,术前均行MRI及扩散加权成像(DWI)检查,收集横轴位T2WI-FS与ADC(b=700 s/mm^(2))图像,以术后病理检查为金标准,分析磁共振T2WI-FS与ADC技术对CC患者LNM与LVSI的评估价值。结果:病理结果显示,120例CC患者中40例存在LNM、无转移80例,T2WI-FS检出LNM 28例、无转移72例,ADC检出LNM 32例、无转移71例,T2WI-FS联合ADC检出LNM 38例,无转移79例,T2WI-FS联合ADC诊断CC患者LNM的准确率97.5%、敏感度95.0%、特异度98.8%、阳性预测值97.4%和阴性预测值97.5%,均高于单独诊断(P<0.05)。病理结果显示,120例CC患者共检出LVSI阳性49例、阴性71例,T2WI-FS检出LVSI阳性37例、阴性60例,ADC检出LVSI阳性39例、阴性61例,T2WI-FS联合ADC检出LVSI阳性46例、阴性69例,T2WI-FS联合ADC诊断CC患者LVSI的准确率95.8%、敏感度93.9%、特异度95.8%、阳性预测值95.8%和阴性预测值95.8%,均高于单独诊断(P<0.05)。结论:磁共振T2WI-FS联合ADC技术评估CC患者LNM与LVSI的价值较高,可为临床治疗方案制订和预后判断提供依据。Objective:To observe the value of T2-weighted imagnetic resonance with fat suppression sequence(T2WIFS)and apparent diffusion coefficient(ADC)technology for evaluating the situations of lymph node metastasis(LNM)and lymph vascular space invasion(LVSI)of patients with cervical cancer(CC).Methods:The clinical data of 120 patients with CC confirmed by pathology who had been given hysterectomy combined with pelvic lymph node dissection in the hospital from January 2018 to September 2023 were analyzed retrospectively.All these patients had received MRI and diffusion-weighted imaging(DWI)before surgery.The images of the transverse T2WI-FS and the ADC of these patients were collected.Based on the postoperative pathological examination as the gold standard,the value of T2WIFS and ADC technology for evaluating the LNM and LVSI of the patients with CC was analyzed.Results:The pathological results showed that 40 of 120 patients with CC had LNM and 80 patients had no LNM.There were 28 patients with LNM detected by T2WI-FS and 72 patients without LNM,there were 32 patients with LNM detected by ADC and 71 patients without LNM,and there were 38 patients with LNM detected by T2WI-FS combined with ADC and 79patients without LNM.The accuracy,the sensitivity,the specificity,the positive predictive value and the negative predictive value of T2WI-FS combined with ADC for diagnosing the LNM of the patients with CC were 97.5%,95.0%,98.8%,97.4%and 97.5%,respectively,which were all significantly higher than those of T2WI-FS or ADC alone(P<0.05).The pathological results showed that there were 49 patients with positive LVSI and 71 patients with negative LVSI in 120 patients with CC.There were 37 patients with positive LVSI and 60 patients with negative LVSI diagnosed by T2WI-FS,there were 39 patients with positive LVSI and 61 patients with negative LVSI diagnosed by ADC,and there were 46 patients with positive LVSI and 69 patients with negative LVSI diagnosed by T2WI-FS combined with ADC.The accuracy,the sensitivity,the specificity,the pos

关 键 词：宫颈癌 淋巴结转移 磁共振 T2加权脂肪抑制序列 表观扩散系数 脉管间隙浸润 评估 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.33[医药卫生—诊断学]