Biotransformation and pharmacological activities of platycosides from Platycodon grandiflorum roots  

作　　者：Lin Shi Tong Cui Xinyue Wang Rina Wu Junrui Wu Yanqun Wang Weiming Wang 

机构地区：[1]College of Food Science,Shenyang Agricultural University,Shenyang 110866,China [2]Institute of Chinese Materia Medica,Heilongjiang Academy of Chinese Medicine Sciences,Harbin 150036,China

出　　处：《Chinese Herbal Medicines》2024年第3期392-400,共9页中草药（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.U20A20400);the Scientific Research Foundation of Heilongjiang Provincial Scientific Research Institutes(No.CZKYF2021A002);Young and middle-aged graduate tutor training program of Shenyang Agricultural University(No.2022-ZZDS-09).

摘　　要：In Northeast China,Goubao pickle is a popular food fermented from the roots of Platycodon grandiflorum as the main material,offering a unique flavor and rich nutritional value.Platycosides in roots of P.grandiflorum may play a crucial role in determining the quality of Goubao pickle through microorganism fermentation.However,biotransfermation of platycosides has not been reviewed during fermentation.In this study,we reviewed platycosides in chemical diversity,metabolic processes in vivo,biotransformation of platycosides in vitro,and pharmacological effects.Finally,we also discussed how to improve the bioactive secondary platycosides we desire by regulating enzymes from microorganisms in the future.

关 键 词：BIOTRANSFORMATION Goubao pickle MICROORGANISMS pharmacological activities platycosides Platycodon grandiflorum(Jacq.)A.DC 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]