High-strength antiswelling adhesive achieves both hemostasis and wound healing  

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作  者:Xin Zhao Jinlong Luo Ying Huang Lei Mu Jueying Chen Zhen Liang Zhanhai Yin Dake Chu Yong Han Baolin Guo 

机构地区:[1]State Key Laboratory for Mechanical Behavior of Materials,Frontier Institute of Science and Technology,Xi'an Jiaotong University,Xi'an,710049,China [2]Department of Plastic Surgery,Xijing Hospital,Air Force Medical University,Xi'an,710032,China [3]Department of Orthopaedics,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China [4]Department of Gastroenterology,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China [5]Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research,College of Stomatology,Xi'an Jiaotong University,Xi'an,710049,China

出  处:《Journal of Pharmaceutical Analysis》2024年第6期781-784,共4页药物分析学报(英文版)

摘  要:Skin is one of the most vulnerable tissues,but there is a lack of injectable bioactive hydrogel dressings,which possess high strength,antiswelling capacity,and wet tissue adhesiveness,but also a rapid gelling process to enable rapid hemostasis,sutureless wound closure,and scarless healing of infected skin wounds[1e5].A new injectable,antibacterial,and multifunctional hydrogel dressings based on poly(citric acid-co-polyethylene glycol)-g-dopamine(PCPD)and amino-terminated Pluronic F127(APF)mi-celles loaded with astragaloside IV(AS)was developed for this pur-pose,as shown in Fig.1A[6].

关 键 词:HEALING WOUND STASIS 

分 类 号:R978.1[医药卫生—药品]

 

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