急性肢体创伤感染病原学分布特点及耐药性分析  

Analysis on pathogenic distribution characteristics and drug resistanceanalysis of acute limb trauma infection

作　　者：张开全[1] 李珍 陈静宜[3] 董浩刚 马彬斌 ZHANG Kaiquan;LI Zhen;CHEN Jingyi;DONG Haogang;MA Binbin(Department of Emergency Trauma Center,Yuxi People's Hospital/Sixth Affiliated Hospital of Kunming Medical University,Yuxi Yunnan 653100,China;Department of Anesthesiology,Yuxi People's Hospital/Sixth Affiliated Hospital of Kunming Medical University,Yuxi Yunnan 653100,China;Department of Clinical Laboratory,Yuxi People's Hospital/Sixth Affiliated Hospital of Kunming Medical University,Yuxi Yunnan 653100,China)

机构地区：[1]玉溪市人民医院/昆明医科大学第六附属医院急诊创伤中心,云南玉溪653100 [2]玉溪市人民医院/昆明医科大学第六附属医院麻醉科,云南玉溪653100 [3]玉溪市人民医院/昆明医科大学第六附属医院医学检验科,云南玉溪653100

出　　处：《云南医药》2024年第4期36-39,共4页Medicine and Pharmacy of Yunnan

摘　　要：目的探讨急性肢体创伤感染病原学分布特点及耐药性分析。方法将本院急诊创伤中心2021年9月-2023年7月间收住院的急性肢体创伤患者创面送检微生物标本纳入数据,分析分离菌株的分布,采用WHONET 5.6软件,根据CLSI 2020年更新标准,分析细菌体外药敏实验数据。结果(1)共送检标本1282分,分离出非重复病原菌220株(17.16%),菌株以革兰阳性菌为主,共111株,占50.45%;(2)分离菌株革兰阳性前3位菌株依次是表皮葡萄球菌、蜡样芽孢杆菌及金黄色葡萄球菌;革兰阴性前3位菌株依次是恶臭假单胞菌、栖稻假单胞菌及约氏不动杆菌。结论提高急性肢体创伤患者微生物标本送检率,及时掌握急性肢体创伤后创面分泌物病原学分布特点及耐药情况,可为临床医生的治疗提供重要依据。Objective To explore the pathogenic distribution characteristics and drug resistance of acute limb trauma infection.Methods Microbial samples from wound surface of acute limb trauma patients admitted to the Emergency Trauma Center of our hospital from September 2021 to July 2023 were included in the data,and the distribution of isolated strains was analyzed.WHONET 5.6 software was used to analyze in vitro drug susceptibility test data according to the updated standards of the American Society for Clinical and Laboratory Standardization(CLSI)in 2020.Results 1.A total of 1282 samples were sent for examination,and 220(17.16%)non-repetitive pathogenic bacteria were isolated.Gram-positive bacteria were the main strain,with a total of 111 strains,accounting for 50.45%;2.The top three gram-positive strains isolated were Staphylococcus epidermidis,Bacillus cereus and Staphylococcus aureus in sequence;The top three gram-negative strains were Pseudomonas putida,Pseudomonas oryzae and Acinetobacter yoshii,respectively.Conclusions Improving the detection rate of microbial specimen submission in patients with acute limb trauma,timely understanding the pathogenic distribution characteristics and drug resistance of wound secretions after acute limb trauma,can provide important basis for clinical treatment.

关 键 词：急性肢体创伤 病原学 耐药性 

分 类 号：R446.5[医药卫生—诊断学]