Comparative Analysis of the Essential Oil of the Underground Organs of Valeriana spp. from Different Countries  

作　　者：Ain Raal Valeriia Kokitko Vira Odyntsova Anne Orav Oleh Koshovyi 

机构地区：[1]Institute of Pharmacy,University of Tartu,Tartu,50411,Estonia [2]Zaporizhzhia State Medical and Pharmaceutical University,Zaporizhzhia,69035,Ukraine [3]Institute of Chemistry,Tallinn University of Technology,Tallinn,12618,Estonia [4]National University of Pharmacy,Kharkiv,61002,Ukraine

出　　处：《Phyton-International Journal of Experimental Botany》2024年第7期1365-1382,共18页国际实验植物学杂志（英文）

基　　金：supported by the European Union in the MSCA4Ukraine Project“Design and Development of 3D-Printed Medicines for Bioactive Materials of Ukrainian and Estonian Medicinal Plants Origin”(ID Number 1232466).

摘　　要：Valeriana officinalis L.is a plant from the Caprifoliaceae family,which is widely distributed in various parts of the world,especially in Europe and Asia.All species of Valeriana are distinguished by their ability to synthesize essen-tial oil,which has a powerful effect on the physiological and mental aspects of the human body.The aim was to study the qualitative and quantitative composition of essential oil from valerian roots,collected in different coun-tries,using the gas chromatography method,and to establish marker compounds for valerian species.13 samples of commercial roots with rhizomes of V.officinalis from nine countries of the world and a sample of Valeriana pratensis and Valeriana stolonifera growing in Ukraine were selected for the study.The essential oil was obtained from dried valerian roots by the distillation method described in the European Pharmacopoeia.To determine the component composition of the essential oils of the selected samples,the methods of gas chromatography with a mass spectrometric detector and capillary gas chromatography were used.The commercial samples of V.offici-nalis from different countries yielded 0.21%–1.03%of essential oil.Only six of 13 samples contained essential oil in an amount that satisfies the requirement of the European Pharmacopoeia standard(not less than 4 mL/kg).150 compounds were identified in the essential oils of 13 samples of V.officinalis essential oils.The range and average content and coefficients of variation of the identified compounds were determined.The principal com-pounds of V.officinalis essential oils were bornyl acetate(1.6%–27.1%),valeranone(0.5%–17.9%),valerenal(0%–14.7%),camphene(0%–14.6%),α-fenchene(0%–10.6%),and valerenic acid(0%–8.5%).The samples of V.pratensis and V.stolonifera yielded rather high levels of essential oil(1.18%and 0.93%,respectively).Three chemotypes of V.officinalis samples were determined-bornyl acetate/valerenal,valeranone,and isovaleric acid.The composition of the three essential oils compared

关 键 词：Valeriana officinalis Valeriana pratensis Valeriana stolonifera volatile compounds TERPENOIDS CHEMOTYPE 

分 类 号：Q94[生物学—植物学]