聚乙烯醇/透明质酸复合导电水凝胶的制备及其传感和抗菌性能  

Preparation and sensing and antimicrobial properties of poly(vinyl alcohol)/hyaluronic acid composite conductive hydrogels

作　　者：王艳敏 丁新波[1] 刘涛[1] 仇巧华 HASAN Md Kamrul 朱灵奇 周家宝 WANG Yanmin;DING Xinbo;LIU Tao;QIU Qiaohua;HASAN Md Kamrul;ZHU Lingqi;ZHOU Jiabao(College of Textile Science and Engineering(International Institute of Silk),Zhejiang Sci-Tech University,Hangzhou 310018,China)

机构地区：[1]浙江理工大学纺织科学与工程学院(国际丝绸学院),杭州310018

出　　处：《现代纺织技术》2024年第8期23-34,共12页Advanced Textile Technology

基　　金：国家自然科学基金项目(37900964);浙江理工大学科研启动基金项目(11150131722120)。

摘　　要：为制备兼具传感和抗菌功能的导电水凝胶,以聚乙烯醇(PVA)和透明质酸(HA)为原料,通过原位聚合和冻融法制得氧化锌/聚(3,4-乙烯二氧噻吩)/聚乙烯醇/透明质酸(ZnO/PEDOT/PVA/HA,简写ZP)导电水凝胶;并对其形貌、结构组成、力学性能、传感性能及其抗菌性能进行分析。结果表明:氧化锌的质量分数在0.3%时,ZP导电水凝胶的电导率最高可达2.91 S/m;ZP导电水凝胶具有良好的拉伸应变性能(≥100%)、灵敏的响应速度(<142 ms)和较好的稳定性(>1000次),能够对人体不同部位的运动信号进行监测识别;此外,ZP导电水凝胶对金黄色葡萄球菌(S.aureus)和大肠杆菌(E.coli)具有良好的抑制效果。该导电水凝胶在柔性可穿戴传感器及医疗健康监测方面具有良好的应用前景。In recent years,people are paying more and more attention to body health detection,and flexible smart wearable sensors have also been developed rapidly.Among them,hydrogel wearable sensors have attracted much attention because of their excellent performance.The hydrogel sensor can be closely applied to the surface of human skin.When the human body moves,it can quickly and accurately output the resistance change caused by the movement in the form of an electrical signal,which is beneficial to our real-time monitoring of human movement.In this paper,poly(vinyl alcohol)(PVA)and hyaluronic acid(HA)were used as the substrates,and poly(3,4-ethylenedioxythiophene)conductive polymer and zinc oxide nanoparticles were used as the functional materials for the preparation of composite conductive hydrogels.Firstly,the zinc oxide/poly(3,4-ethylenedioxythiophene)/hyaluronic acid/poly(vinyl alcohol)composite conductive hydrogels(ZnO/PEDOT/PVA/HA)with strain sensing response and antimicrobial properties were prepared by in situ polymerization and cyclic freeze-thawing method by adding 3,4-ethylenedioxythiophene(EDOT)monomer to ZnO/hyaluronic acid/poly(vinyl alcohol)(ZnO/PVA/HA)hydrogel solution after adding zinc oxide(ZnO)nano-polymer prepared by the mechanically assisted thermal method to poly(vinyl alcohol)/hyaluronic acid(PVA/HA)hydrogel solution with different ratios.The morphology and chemical composition of the ZnO nanoparticles and the conductive hydrogel were characterized by using field emission scanning electron microscopy(FE-SEM),Fourier transform infrared spectroscopy(FTIR)and X-ray powder diffractometer,respectively.The mechanical,sensing and antimicrobial properties of the hydrogels were also tested and analyzed,and the optimal parameter ratio of the composite hydrogels was determined as m(ZnO/EDOT/PVA/HA)=(0.03∶0.1∶(1∶9)).The results showed that the addition of ZnO further improved the conductivity of the hydrogel,and the conductivity of the ZnO/PEDOT/PVA/HA(ZP)conductive hydrogel could reach 2.91 S/m,which w

关 键 词：导电水凝胶 传感性能 柔性可穿戴传感器 抗菌性能 

分 类 号：TB332[一般工业技术—材料科学与工程]