正念减压法联合度洛西汀在恶劣心境患者中的应用效果  

Effect of mindfulness-based stress reduction combined with Duloxetine in patients with dysthymia

作　　者：贺果扬 李春芳 欧阳伟 HE Guoyang;LI Chunfang;OUYANG Wei(Department of Psychiatry,Pingxiang NO.2 People's Hospital,Jiangxi Province,Pingxiang 337000,China)

机构地区：[1]江西省萍乡市第二人民医院精神科,江西萍乡337000

出　　处：《中国当代医药》2024年第23期49-53,共5页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202212089)。

摘　　要：目的观察并分析对恶劣心境患者应用正念减压法联合度洛西汀治疗的效果。方法选取2021年9月至2023年8月萍乡市第二人民医院精神科收治的60例患者作为研究对象,按照门诊号尾数单双号将其分为对照组(30例)与观察组(30例)。对照组患者采用药物度洛西汀治疗方法,观察组患者采用正念减压法+度洛西汀治疗方法。比较两组患者临床疗效、抑郁情绪、汉密尔顿抑郁量表17项版(HAMD-17)、抑郁自评量表(SDS)评分减分值、精神状态以及健康程度评分。结果在应用联合方案后,观察组临床疗效高于对照组;HAMD-17评分、SDS评分减分值高于对照组,且HAMD-17评分、SDS评分低于对照组;精神状态评分低于对照组,健康程度评分高于对照组,差异有统计学意义(P<0.05)。结论对恶劣心境患者应用正念减压法联合度洛西汀治疗,可更好地改善其抑郁情绪,可行性良好,值得应用推广。Objective To observe and analyze the effect of mindfulness-based stress reduction combined with Duloxetine on patients with dysthymia.Methods A total of sixty patients admitted to the Department of Psychiatry,Pingxiang NO.2 People's Hospital from September 2021 to August 2023 were selected as the study objects and they were divided into control group(30 cases)and observation group(30 cases)based on the last digit of the outpatient number,odd or even.The control group patients were treated with the drug Duloxetine,while the observation group patients were treated with mindfulness decompression and Duloxetine.The clinical efficacy,depressive mood,Hamilton depression scale 17(HAMD-17),self rating depression scale(SDS)score reduction,mental state,and health status scores were compared between two groups of patients.Results After applying the combined regimen,the clinical efficacy of the observation group was higher than that of the control group;The HAMD-17 and SDS scores were higher than the control group,and the HAMD-17 and SDS scores were lower than the control group,and the mental state score was lower than that of the control group,and the health level score was higher than that of the control group,and the differences were statistically significant(P<0.05).Conclusion The application of mindfulness decompression combined with Duloxetine in the treatment of patients with severe mood disorders can better improve their depressive mood,which is feasible and worth promoting.

关 键 词：恶劣心境 度洛西汀 正念减压法 抑郁情绪 精神状态 

分 类 号：R395[哲学宗教—心理学]