慢性阻塞性肺疾病与消化系统疾病关系及其机制的中西医研究新进展  

Research Progress of Traditional Chinese and Western Medicine on the Relationship between Chronic Obstructive Pulmonary Disease and Digestive System Diseases and Its Mechanism

作　　者：王飞梅 付生渊 蔡成森[2] 付立娜 于健健 王珺[2] WANG Feimei;FU Shengyuan;CAI Chengsen;FU Lina;YU Jianjian;WANG Jun(Shandong University of Traditional Chinese Medicine,Jinan 250014,China;Department of Respiratory and Critical Care Medicine,the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250001,China)

机构地区：[1]山东中医药大学,山东省济南市250014 [2]山东中医药大学第二附属医院呼吸与危重症医学科,山东省济南市250001

出　　处：《实用心脑肺血管病杂志》2024年第9期134-140,共7页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：国家中医药管理局-山东省卫生健康委员会共建中医药科技项目(GZY-KJS-SD-2023-048);山东省中医药科技项目(Q-2023041)。

摘　　要：慢性阻塞性肺疾病(COPD)是常见的慢性气道疾病,其发病率和病死率高,给患者及家属带来极大的负担。研究表明,消化系统症状是COPD患者的常见肺外全身表现,且随着COPD严重程度加重其逐渐恶化。西医认为,COPD与胃食管反流病(GERD)、消化性溃疡(PU)、胃肠功能紊乱、非酒精性脂肪性肝病(NAFLD)有关。中医认为,脾肺为相生关系,母病及子,子病及母;肺肝为相克关系,相乘相侮,肺病及肝,肝病及肺;肺与大肠相表里,肺气肃降,大肠传导,互相影响。近年来COPD与消化系统疾病关系的研究越来越多,而了解疾病之间的相互作用才能更好地治疗疾病,本文总结了COPD与消化系统疾病关系及其机制的中西医研究新进展,以期为今后预防和治疗COPD并发消化系统疾病提供理论依据。Chronic obstructive pulmonary disease(COPD)is a common chronic airway disease with high morbidity and mortality,which brings great burden to patients and their families.Studies have shown that digestive symptoms are a common extrapulmonary systemic manifestation of COPD patients,and with the severity of COPD,the digestive symptoms worsened.Western medicine currently believes that COPD is related to gastroesophageal reflux disease(GERD),peptic ulcer(PU),gastrointestinal dysfunction,and non-alcoholic fatty liver disease(NAFLD).Traditional Chinese medicine believes that the spleen and lung are interdependent,mother-organ disorder can involve its child-organ,child-organ disorder can involve its mother-organ;the lung and liver have a mutually restrictive relationship,that is over-restriction and reverse restriction,and lung disease can affect the liver,while liver disease can affect the lung;the lung and the large intestine are interior-exteriorly related,the impaired lung Qi and the conduction of the large intestine interact with each other.In recent years,more and more studies have been conducted on the relationship between COPD and digestive system diseases,while understanding the interactions between diseases can lead to better treatment.This paper summarized the research progress of traditional Chinese and western medicine on the relationship between COPD and digestive system diseases and its mechanism,in order to provide theoretical basis for the prevention and treatment of COPD complicated with digestive system diseases in the future.

关 键 词：肺疾病 慢性阻塞性 胃肠疾病 胃食管反流病 消化性溃疡 非酒精性脂肪性肝病 综述 

分 类 号：R563.9[医药卫生—呼吸系统] R57[医药卫生—内科学]