CT动态增强扫描联合纹理分析对结肠癌的评估效果  

Evaluation Effect of Colon Cancer Using Dynamic Enhanced CT Scanning Combined with Texture Analysis

作　　者：李长海 LI Changhai(Department of Radiology,the Fourth People’s Hospital of Xinyang,Xinyang 464100,China)

机构地区：[1]信阳市第四人民医院放射科,河南信阳464100

出　　处：《河南医学研究》2024年第16期2969-2972,共4页Henan Medical Research

摘　　要：目的分析CT动态增强扫描联合纹理分析对结肠癌的评估价值。方法前瞻性研究,纳入医院2021年1月至2023年12月收治的93例高度疑似结肠癌患者作为研究对象,所有患者均在入院后接受CT动态增强扫描、纹理分析,以结肠镜下活检结果为金标准,分析CT动态增强扫描联合纹理分析对结肠癌的评估价值。结果93例高度疑似结肠癌患者,经结肠镜下活检证实为结肠癌69例,占比74.19%,剩余24例均为溃疡性结肠炎,占比25.81%。结肠癌患者静脉期P90、静脉期熵、延迟期变异数差均高于非结肠癌患者(P<0.05),纹理分析各参数对结肠癌评估的曲线下面积均>0.7,静脉期P90、静脉期熵、延迟期变异数差最佳截断值分别取82.940、2.820、2.845时,可获取理想的敏感度及特异度。CT动态增强扫描结果、纹理分析与结肠镜下活检结果的一致性一般(Kappa值分别为0.565、0.585,P均<0.001),联合扫描与结肠镜下活检结果的一致性好(Kappa=0.801,P<0.001)。联合评估的敏感度、准确度及阴性预测值均高于CT动态增强扫描、纹理分析(P<0.05)。结论CT动态增强扫描联合纹理分析评估结肠癌与结肠镜下活检一致性较好,可提高对结肠癌的评估价值。Objective To analyze the evaluation value of dynamic enhanced CT scanning combined with texture analysis for colon cancer.Methods A prospective study was conducted on 93 highly suspected colon cancer patients admitted to the hospital from January 2021 to December 2023.All patients underwent dynamic enhanced CT scanning and texture analysis after admission,with colonoscopy biopsy results as the gold standard.The evaluation value of CT dynamic enhanced scanning combined with texture analysis for colon cancer was analyzed.Results Among the 93 highly suspected patients with colon cancer,69 cases were confirmed by colonoscopy biopsy,accounting for 74.19%.The remaining 24 cases were all ulcerative colitis,accounting for 25.81%.Colon cancer patients had higher venous phase P90,venous phase entropy,and delayed phase variance than non colon cancer patients(P<0.05).The area under curve of texture analysis parameters for evaluating colon cancer was greater than 0.7.The optimal cutoff values for venous phase P90,venous phase entropy,and delayed phase variance were 82.940,2.820 and 2.845,respectively.Ideal sensitivity and specificity could be obtained.The results of dynamic enhanced CT scan and texture analysis were generally consistent with the results of colonoscopy biopsy(Kappa values were 0.565 and 0.585,P<0.001),while the results of combined scan and colonoscopy biopsy were better consistent(Kappa=0.801,P<0.001).The sensitivity,accuracy,and negative predictive values of joint evaluation were higher than those of CT dynamic enhanced scanning and texture analysis(P<0.05).Conclusion The combination of dynamic enhanced CT scanning and texture analysis in evaluating colon cancer has good consistency with colonoscopy biopsy,which can improve the evaluation value of colon cancer.

关 键 词：结肠癌 结肠炎 CT动态增强扫描 纹理分析 

分 类 号：R445.3[医药卫生—影像医学与核医学]