低危孕妇孕中期子宫动脉搏动指数、孕前体重指数及平均动脉压联合预测不良妊娠结局的价值  

Value of Uterine Artery Pulsatility Index,Pre-pregnancy Body Mass Index and Mean Artery Pressure in Predicting Adversepregnancy Outcomes in Low-risk Pregnant Women in the Second Trimester

作　　者：刘晴 李锦巍 王锋[1] 徐静[1] 崔利娜[1] 刘俊香[1] 袁翱龙 LIU Qing;LI Jinwei;WANG Feng;XU Jing;CUI Lina;LIU Junxiang;YUAN Aolong(Department of Obstetrics,Luohe Central Hospital,Luohe 462000,China)

机构地区：[1]漯河市中心医院产科,河南漯河462000

出　　处：《河南医学研究》2024年第16期3000-3003,共4页Henan Medical Research

基　　金：河南省医学科技攻关计划联合共建项目(2018021027)。

摘　　要：目的评估孕中期平均动脉压(MAP)、孕前体重指数(BMI)联合子宫动脉搏动指数(PI)在预测低危孕妇不良妊娠结局中的价值。方法回顾性分析148例孕21~25周在漯河市中心医院产前门诊就诊的低危孕妇的人口统计学、临床、子宫动脉多普勒超声参数和妊娠结局,并根据妊娠结局分为正常妊娠结局组(99例)和不良妊娠结局组(49例)。结果单因素分析结果显示,正常妊娠结局组与不良妊娠结局组患者在年龄、孕前BMI、MAP、子宫动脉PI差异有统计学意义(P<0.05),孕次、实际孕周、双顶径、股骨长、羊水最大深度、子宫动脉RI、子宫动脉S/D、终止孕周等差异无统计学意义(P>0.05)。多因素分析结果显示孕前BMI、平均动脉压(MAP)、子宫动脉PI是不良妊娠结局的影响因素,据此构建不良妊娠结局预测模型,受试者工作特征(ROC)曲线分析显示,该模型预测不良妊娠结局的曲线下面积(AUC)为0.730,敏感度81.63%,特异度55.56%。结论孕中期子宫动脉PI联合孕前BMI、MAP对低危孕妇不良妊娠结局有一定的临床预测价值。Objective To assess the value of second trimester mean artery pressure(MAP),pre-pregnancy body mass index(BMI)combined with uterine artery pulsatility index(PI)in predicting adverse pregnancy outcomes in low-risk pregnant women.Methods The demographic,clinical,uterine artery Doppler ultrasound parameters and pregnancy outcomes of 148 low-risk pregnant women admitted to the prenatal clinic of our hospital at 21-25 weeks of gestation were retrospectively analyzed and divided into two groups according to their pregnancy outcomes,the normal pregnancy outcome group(99 patients)and the adverse pregnancy outcome group(49 patients).Results Univariate analysis revealed significant differences in age,pre-pregnancy BMI,MAP,and uterine artery PI(P<0.05),and there were no significant differences in parameters such as times of pregnancy,actual gestational weeks,biparietal diameter,femoral length,maximum depth of amniotic fluid,uterine artery resistance index(RI),uterine artery S/D,and termination of gestational weeks between the normal pregnancy outcome group and the adverse pregnancy outcome group(P>0.05).Multivariate analysis showed that pre-pregnancy BMI,MAP,and uterine artery PI were significant factors affecting adverse pregnancy outcomes.Based on these findings,a prediction model for adverse pregnancy outcomes was constructed.Receiver operating characteristic(ROC)curve analysis showed that the area under the curve(AUC)of the model to predict adverse pregnancy outcomes was 0.730,with a sensitivity of 81.63%,and a specificity of 55.56%.Conclusion Second trimester uterine artery PI combined with pre-pregnancy BMI and MAP has certain clinical predictive value for adverse pregnancy outcomes in low-risk pregnant women.

关 键 词：低危孕妇 孕中期 不良妊娠结局 

分 类 号：R714.1[医药卫生—妇产科学]