基于Gephi对抑郁症中医证型相关临床研究的可视化分析  

Visual analysis of clinical research on traditional Chinese medicine syndrome types of depression based on Gephi

作　　者：杜仪[1] 刘可佳 韩超汝 徐帅 李娟娟 赵静洁[1] DU Yi;LIU Kejia;HAN Chaoru;XU Shuai;LI Juanjuan;ZHAO Jingjie(Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院,北京100050

出　　处：《军事医学》2024年第7期537-542,共6页Military Medical Sciences

基　　金：国家自然科学基金项目(82004109),北京市自然科学基金项目(7204250),北京市医管局科研培育计划(PZ2020001)。

摘　　要：目的通过对现有抑郁症中医辨证分型相关的临床研究文献进行分析,归纳总结抑郁症的常见中医证型及证候特点,为抑郁症的中医证型和辨证研究提供辨证分型依据。方法系统检索中国知网(CNKI)、中国生物医学文献服务系统(SinoMed)、维普中文期刊服务平台(VIP)及万方医学网中文期刊库(WanFang)抑郁症中医辨证相关的文献,对命中文献进行整理和分析,并使用Gephi软件进行可视化分析。结果研究共筛选出符合标准的文献262篇,2010年以后年均发文量超过10篇。中医辨证人次排名前5的证型分别为:肝气郁结型、肝郁脾虚型、心脾两虚型、肝郁痰阻型及肝郁肾虚型,脏腑辨证主要涉及肝、脾、心、肾、胆,证型虚实分类以实证为主,关联性最强的为肝气郁结证,虚证关联性最强的是心脾两虚证,虚实夹杂证关联性最强的是肝郁脾虚证。结论抑郁症中医证型相关文献发表量呈波动上升趋势。抑郁症的发生发展与多脏腑功能失调相关,肝郁是其主要证候核心,且可能贯穿抑郁症发病全过程。Objective To summarize the common traditional Chinese medicine(TCM)syndrome types and syndrome characteristics of depressive disorder(DD)by analyzing the existing clinical research literature,and to provide a basis for TCM syndrome classification and research on DD.Methods The documents related to TCM syndrome classification of DD were retrieved systematically from China National Knowledge Infrastructure(CNKI),China Biology Medicine Literature Service System(SinoMed),China Science and Technology Journal Database(VIP)and China Academic Journals Full⁃text Database(WanFang).The literature was organized and analyzed,and Gephi software was used to do the visual analysis.Results A total of 262 literature that met the criteria were included in the study.The annual average number of publications exceeds 10 articles since 2010.The top 5 syndrome types in TCM were Liver Qi Stagnation(LQS)type,Liver Stagnation and Spleen Deficiency(LSSD)type,Heart and Spleen Deficiency(HSD)type,Liver Stagnation and Phlegm Obstruction type and Liver Stagnation and Kidney Deficiency type,viscera syndrome classification mainly involved Liver,Spleen,Heart,Kidney and Gallbladder.The main syndrome type based on deficiency⁃excess syndrome classification was excess type.The strongest correlation of excess type was LQS,the strongest correlation of deficiency types was HSD,and the strongest correlation of deficiency and excess mixed syndrome type was LSSD.Conclusion The publication volume of literature related to TCM syndrome types of DD shows a fluctuating upward trend.The occurrence and development of DD are related to dysfunction of multiple organs,and liver stagnation is the core syndrome,which may run through the entire process of DD.

关 键 词：抑郁症 证型 证候 肝气郁结 心脾两虚 

分 类 号：R277.7[医药卫生—中医学]