植物HIPP家族蛋白结构和功能研究进展  

Research Advances of Structure and Function of HIPP Family in Plants

作　　者：张雅琦 戎福喜 沈雨欣 洪哲源 张蓝天 武亮 Yaqi Zhang;Fuxi Rong;Yuxin Shen;Zheyuan Hong;Lantian Zhang;Liang Wu(Hainan Institute of Zhejiang University,Sanya 572025,China;College of Agriculture and Biotechnology,Zhejiang University,Hangzhou 310000,China)

机构地区：[1]浙江大学海南研究院,三亚572025 [2]浙江大学农业与生物技术学院,杭州310000

出　　处：《植物学报》2024年第4期659-670,共12页Chinese Bulletin of Botany

基　　金：三亚市科技创新专项(No.2022KJCX48);海南专项博士研究生科学研究基金(No.0201-6602-C22201,No.0201-6602-C22202)。

摘　　要：重金属相关异戊二烯化植物蛋白HIPP是一类含有金属结合结构域(HMA)和C端异戊二烯化基序的金属伴侣蛋白。该文总结了模式植物中HIPP蛋白的结构特征,阐述了植物HIPP蛋白家族参与的重金属稳态和解毒机制,揭示了其在植物生长发育和应对环境变化(生物和非生物胁迫)中的潜在意义,以期为HIPP蛋白家族的后续研究提供启示。Heavy metal-associated isoprenylated plant proteins(HIPPs)are a class of proteins characterized by the presence of heavy metal-associated domains(HMA)and C-terminal isoprenylation motifs in plants.Here,we introduce the structural characteristics of the HIPPs,review their potential roles in plant development and response to environ-mental changes(including biotic and abiotic stresses)as well as discuss their working mechanisms underlying their par-ticipation in heavy-metal homeostasis and detoxification.This comprehensive overview aims to provide valuable insights for future research on the HIPP family across diverse plant species.

关 键 词：HIPPs HMA 重金属 

分 类 号：Q945[生物学—植物学]