水杨酸及其复配体系的抑真菌性能  

Antifungal Performance of Salicylic Acid and Its Compound System

作　　者：许雯雯 陈韦韦 袁旻嘉 XU Wenwen;CHEN Weiwei;YUAN Minjia(Shanghai Qiran Biotechnology Co.,Ltd.,Shanghai 201702,China;Shanghai Jinjia Technology Co.,Ltd.,Shanghai 201210,China)

机构地区：[1]上海其然生物科技有限公司,上海201702 [2]上海缙嘉科技有限公司,上海201210

出　　处：《香料香精化妆品》2024年第4期18-23,共6页Flavour Fragrance Cosmetics

摘　　要：采用微生物挑战试验方法,以水杨酸为研究对象,考察单独使用水杨酸和复配对羟基苯乙酮、1,2-己二醇、p-茴香酸及覆盆子酮的抑真菌性能。结果表明:随着水杨酸质量分数的增加,pH的降低,其抑真菌能力增强。在水杨酸质量分数为0.5%,体系pH小于5.0时,复配质量分数0.3%~0.5%对羟基苯乙酮、0.05%~0.2%p-茴香酸、0.5%的覆盆子酮以及同时复配0.3%对羟基苯乙酮和0.3%1,2-己二醇时,均能提高抑真菌效果。水杨酸复配的研究结果可为化妆品防腐体系给出指导性建议。Salicylic acid as the main research object,the antifungal performance of salicylic acid and blending p-hydroxyacetophenone,1,2-hexanediol,p-anisic acid and raspberry ketone was studied by microbial challenge test.Results showed that with the increase of salicylic acid mass fraction and the decrease of pH,the effect of antifungal was enhanced.When the mass fraction of salicylic acid was 0.5%and the pH is less than 5.0,the addition of 0.3%-0.5%p-hydroxyacetophenone,0.05%-0.2%p-anisic acid,0.5%raspberry ketone,and blending 0.3%p-hydroxyacetophenone and 0.3%1,2-hexanediol all in mass fraction could improve the antifungal effect.The results of salicylic acid compounding can provide guidance for the preservative system of cosmetics.

关 键 词：微生物挑战试验 水杨酸 对羟基苯乙酮 1 2-己二醇 p-茴香酸 覆盆子酮 复配 抑真菌能力 

分 类 号：TQ658[化学工程—精细化工]