南通市肿瘤医院2002—2017年胃癌患者生存分析  

Survival analysis of gastric cancer patients in Nantong Tumor Hospital from 2002 to 2017

作　　者：陈铭睿 陈海珍[2] 蔡波[1] 林玲[1] 糜跃萍[1] 韩颖颖[1] 凡丽芸 张爱红[4] 王书兰 徐红[1] 陈建国[2] CHEN Ming-rui;CHEN Hai-zhen;CAI Bo;LIN Ling;MI Yue-ping;HAN Ying-ying;FAN Li-yun;ZHANG Ai-hong;WANG Shu-lan;XU Hong;CHEN Jian-guo(Nantong Municipal Center for Disease Control and Prevention,Nantong Jiangsu 226007,China;不详)

机构地区：[1]南通市疾病预防控制中心,江苏南通226007 [2]南通市肿瘤医院南通大学附属肿瘤医院 [3]南通市通州区疾病预防控制中心 [4]如东县疾病预防控制中心 [5]如皋市疾病预防控制中心

出　　处：《江苏预防医学》2024年第3期297-299,351,共4页Jiangsu Journal of Preventive Medicine

摘　　要：目的了解南通市肿瘤医院2002—2017年胃癌患者的生存情况。方法基于南通市肿瘤医院2002—2017年胃癌病例资料,采用主动随访与被动随访相结合的方法进行生存随访,随访截止日期为2020年12月31日。失访率采用χ^(2)检验进行差异比较;用寿命表法计算观察生存率,用Kaplan-Meier法绘制生存曲线,单因素分析采用Log-rank检验。结果选取2002—2017年南通市肿瘤医院南通户籍胃癌患者6078例,男性4314例(70.98%),女性1764例(29.02%),随访成功率98.21%(5969例),平均发病年龄(63.47±11.09)岁,以65~<75岁最为多见(35.42%),其次为55~<65岁(30.57%)。胃癌患者平均生存时间为5.47年,1、3、5、10年观察生存率分别为65.05%、40.92%、34.10%、27.07%,男性分别为65.61%、40.70%、33.68%、26.19%,女性分别为63.68%、41.46%、35.12%、29.20%,差异无统计学意义(χ^(2)=1.849,P=0.474);<45岁、45~<55岁、55~<65岁、65~<75岁和≥75岁5年生存率分别为39.50%、38.84%、38.65%、33.26%、20.41%,差异有统计学意义(χ^(2)=149.699,P<0.01)。2002—2009年及2010—2017年两个时期的5年生存率分别为35.60%及31.61%,差异有统计学意义(χ^(2)=7.233,P<0.01)。结论南通市2002—2017年胃癌患者生存率较低,可通过胃癌筛查、早诊早治提高胃癌患者生存率,延长生存时间。Objective To investigate the survival of gastric cancer patients in Nantong Tumor Hospital from 2002 to 2017.Methods Based on medical records of gastric cancer patients admitted to Nantong Tumor Hospital from 2002 to 2017,and the survival follow-up was performed using active and passive follow-up until December 31,2020.Differences in rate of loss to follow-up were compared using chi-square test,and the survival rate was estimated using the life-table method.Survival curve was plotted using the Kaplan-Meier method,and univariate analysis was performed using log-rank test.Results A total of 6078 gastric cancer patients with household registration in Nantong City that were admitted to Nantong Tumor Hospital from 2002 to 2017 were recruited,including 4314 men(70.98%)and 1764 women(29.02%).The subjects had a 92.21%rate of successful follow-up(5969 cases),and a mean age of(63.47±11.09)years,with the highest proportion at age of 65 to 75 years(35.42%),followed by at ages of 55 to 65 years(30.57%).The mean survival period of gastric cancer patients was 5.47 years,and the observed 1-,3-,5-and 10-year survival rates were 65.05%、40.92%、34.10%and 27.07%,with 65.71%,40.70%,33.68%and 26.19%among men and 63.68%,41.46%,35.12%and 29.20%among women(χ^(2)=1.849,P=0.474).The 5-year survival rates were 39.50%,38.84%,38.65%,33.26%and 20.41%among gastric cancer patients at ages of<45 years,45 to 55 years,55 to 65 years,65 to 75 years and 75 years and older(χ^(2)=149.699,P<0.01).The 5-year survival rates of gastric cancer patients were 35.60%and 31.61%during the period between 2002 and 2009 and between 2010 and 2017(χ^(2)=7.233,P<0.01).Conclusions The survival rate was low among gastric cancer patients in Nantong City from 2002 to 2017.Screening,early diagnosis and early treatment of gastric cancer may improve the survival rate and prolong the survival period among gastric cancer patients.

关 键 词：胃癌 肿瘤登记 生存分析 

分 类 号：R195[医药卫生—卫生统计学]