《外科正宗》治疗乳腺疾病的用药规律分析  

Analysis of the Medication Rules of"Surgery Authentic"for Treating Breast Diseases based on Data Mining

作　　者：吕威林 刘磊 孙恒 王寒笑 李文娟 李敬伟 LYU Weilin;LIU Lei;SUN Heng;WANG Hanxiao;LI Wenjuan;LI Jingwei(Taihe County Hospital of Traditional Chinese Medicine Affiliated of Anhui University of Chinese Medicine,Anhui Taihe 236600,China)

机构地区：[1]安徽中医药大学附属太和中医院,安徽太和236600

出　　处：《中医药临床杂志》2024年第8期1519-1523,共5页Clinical Journal of Traditional Chinese Medicine

基　　金：安徽省中医药大学临床科研重点项目(2023LCTH08);阜阳市重点研究与开发计划项目临床医学转化专项(FYZDYF2023LCYX029)。

摘　　要：目的:对《外科正宗》进行数据挖掘,分析归纳治疗乳腺疾病的用药方法及规律,以期为临床治疗乳腺疾病提供新的思路参考。方法:借助中医传承辅助平台(V2.5),对《外科正宗》进行数据挖掘。将书中治疗乳腺疾病的药物,从性味归经、用药频数、优势药对及关联规则等方面进行统计分析。结果:经统计共有28首方剂及72味中药。72味中药中有18味中药使用频次较高。药性以温、寒性、平性为主。药味以甘、辛、苦味为主。归经以肝经、脾经为主。频次≥6的药物组合共有25组。熵聚类分析得到2首新处方。结论:《外科正宗》治疗乳腺疾病善用疏肝理气、补脾胃益气血之法,体现陈实功主张的“夫乳病者,乳房阳明经所司,乳头厥阴肝经所属”及“治疮全赖脾土”的学术思想。Objective:To conduct data mining on“Surgery Authentic”and analyze and summarize the medication methods and rules for treating breast diseases,in order to provide new ideas and references for the clinical treatment of breast diseases.Methods:With the help of the TCM inheritance auxiliary platform(V2.5),data mining was conducted on“Surgery Authentic”.The drugs for treating breast diseases in the book were statistically analyzed in terms of nature,taste,meridians,medication frequency,dominant drug pairs and association rules.Results:According to the statistics,there were 28 prescriptions and 72 Chinese medicines.Among the 72 Chinese medicines,18 Chinese medicines were used more frequently.The medicinal properties were mainly warm,cold and neutral.The medicinal taste was mainly sweet,pungent and bitter.The meridians were mainly liver meridian and spleen meridian.There were 25 groups of drug combinations with a frequency of≥6.Entropy cluster analysis obtained 2 new prescriptions.Conclusion:The Authen-tic Surgery is good at using the methods of soothing the liver and regulating Qi,tonifying the spleen and stomach and replenishing Qi and blood to treat breast diseases,which reflects Chen Shigong’s academic ideas that“breast diseases are controlled by the Yangming meridian of the breast and the Jueyin liver meridian of the nipple”and“the treatment of sores depends entirely on the spleen and earth”.

关 键 词：外科正宗 乳腺疾病 数据挖掘 用药规律 

分 类 号：R269[医药卫生—中西医结合]