新疆阿克苏市2019-2022年多中心500例胸膜结核患者的临床特征分析  

Clinical characteristics of 500 patients with pleural TB in Aksu City,Xinjiang during 2019-2022

作　　者：岳小萍 YUE Xiaoping(The Infectious Disease Hospital of Aksu of Xinjiang Uygur Autonomous Region,Aksu,Xinjiang,843000,China)

机构地区：[1]新疆维吾尔自治区阿克苏市传染病医院,新疆阿克苏843000

出　　处：《新疆医学》2024年第4期452-455,共4页Xinjiang Medical Journal

摘　　要：目的分析新疆阿克苏市2019年-2022年多中心500例胸膜结核患者的临床特征。方法回顾性分析新疆阿克苏市2019年1月-2022年1月多中心500例胸膜结核患者的临床资料,分析患者的流行病学、临床特征、治疗及随访结果。结果500例胸膜结核患者中,男性较多,为370例(74.00%),女性仅130例(26.00%);<45岁有220例,发病率最高,为44.00%;春秋季节为疾病高发季节,共408例,占比81.60%;居住地为农村者较多(388例),发病率为77.60%;胸腔积液单侧渗出者较多(455例),占比91.00%,其中单左侧渗出265例(53.00%),单右侧渗出190例(38.00%)。临床表现中,咳嗽(483例)、发热(451例)为主要症状,发病率为96.60%、90.20%;胸腔镜下病理特征中,胸膜黏连(372例)、胸膜增厚(235例)、充血(196例)较常见,发病率分别为74.40%、47.00%、39.20%;胸膜活检病理特征中,肉芽肿性炎(340例)发病率最高,为68.00%。500例患者治疗过程中出现药物性肝损伤99例,发生率为19.80%(99/500),类赫氏反应6例,发生率为1.20%(6/500)。随访1年,胸膜结核复发3例,复发率为0.60%(3/500)。结论新疆阿克苏市2019年-2022年多中心500例胸膜结核患者以男性青壮年为主,多发于春秋季节,以胸腔积液单侧渗出为主,临床可依据患者的临床表现及特征进行诊疗。Objective To analyze the clinical characteristics of 500 patients with pleural TB in Aksu City,Xinjiang from 2019 to 2022.Methods The clinical data of 500 pleural TB patients were analyzed from January 2019 to January 2022,and the epidemiology,clinical characteristics,treatment and follow-up results were analyzed.Results Of the 500 cases,370 cases of pleural tuberculosis,370 cases were male,and only 130 cases(26.00%)were female.There were 220 cases<45 years old,the highest incidence(44.00%).The spring and autumn season was the season of high incidence of diseases,with 408 cases,accounting for 81.60%.Most of them lived in rural areas(388 cases),and the incidence was 77.60%.There were 455 cases(91.00%)with unilateral effusion of pleural effusion,among which 265 cases(53.00%)had unilateral effusion on the left side and 190 cases(38.00%)had unilateral effusion on the right side.In clinical manifestations,cough(483 cases)and fever(451 cases)were the main symptoms,with the incidence of 96.60% and 90.20%;in thoracoscopic pathological features,pleural adhesion(372 cases),pleural thickening(235 cases)and congestion(196 cases)were common,with the incidence of 74.40%,47.00%and 39.20%,respectively.Among the pathological characteristics of pleural biopsy,granulomatosis(340 cases)had the highest incidence of 68.00%.Drug induced liver injury occurred in 99 of the 500 patients during treatment,with an incidence of 19.80%(99/500),and Hersher-like reaction occurred in 6 patients,with an incidence of 1.20%(6/500).After 1 year of follow-up,3 cases of pleural tuberculosis recurred,with a recurrence rate of 0.60%(3/500).Conclusion 500 patients with pleural tuberculosis from 2019 to 2022 in Aksu City,Xinjiang Province,China were mainly male young adults,mostly in spring and autumn,and unilateral exudation of pleural effusion.Clinical diagnosis and treatment can be carried out according to the clinical manifestations and characteristics of patients.

关 键 词：新疆阿克苏市 胸膜结核 临床特征 胸腔积液 

分 类 号：R521[医药卫生—内科学]