HARRT治疗对腹部手术患者围手术期的影响  

The influence of HARRT treatment on perioperative period of patients undergoing abdominal surgery

作　　者：马安舍 宋思凯 唐光平 MA Anshe;SONG Sikai;TANG Guangping(The second department of surgery,The Eighth Affiliated Hospital of Xinjiang Medical University,Urumqi,830049,China;The abdominal surgery,The Third People's Hospital of Xinjang Uygur Autonomous Region,Urumqi,830099,China)

机构地区：[1]新疆医科大学第八附属医院外二科,乌鲁木齐830049 [2]新疆维吾尔自治区第三人民医院腹部外科,乌鲁木齐830099

出　　处：《新疆医学》2024年第4期456-458,465,共4页Xinjiang Medical Journal

基　　金：新疆医科大学第八附属医院院内课题(项目编号:QLY-KY-2018007)。

摘　　要：目的探讨高效抗逆转录病毒治疗(Hidghly Active Anti-Retroviral Therapy,HAART)治疗对进行腹部手术的获得性免疫缺陷综合征(Acquired Immune Deficiency Syndrome,AIDS)患者围手术期相关指标的影响,为临床腹部外科手术的AIDS患者进行HAART治疗提供参考。方法收集新疆医科大学第八附属医院2019年1月-2022年1月收住的腹部手术的HIV患者的病例、辅助检查资料,对比规律进行HAART治疗与非规律服药的HIV患者不同状态下手术时间、切口愈合情况、排气排便时间及肝肾功等相关指标的差异。结果共收集病例60份,其中规律服药组及非规律服药组各30份,对比分析显示,两者的术后排气时间、排便时间、术前白蛋白、术后2 d及7 d白蛋白在两组比较中,有着统计学的差异(P<0.01)。结论规律进行HAART治疗的HIV患者术前白蛋白及CD4含量明显要优于未规律服药组,规律服药的腹部手术患者术后能有更短的胃肠道功能恢复时间,围手术期肝肾功并未受到明显干扰,在切口愈合方面,两组并未能有明显差异。Objective To investigate the effect of Highly Active Anti-Retroviral Therapy(HAART)on perioperative indexes in patients with Acquired Immune Deficiency Syndrome(AIDS)undergoing abdominal surgery,and to provide reference for HAART in AIDS patients undergoing abdominal surgery.Methods Collected datum about HIV patients undergoing abdominal surgery,taking HAART regularly or irregularly,in The Eighth Affiliated Hospital of Xinjiang Medical University from January 2019 to January 2022.The differences of operation time,wound healing,exhaust and defecation time,liver and kidney function and other related auxiliary examination indexes under different conditions were collected and analyzed.Results A total of 60 cases were included,including 30 of the regular medication group and 30 of the irregular medication group.The final analysis showed that the postoperative exhaust time,defecation time,albumin before surgery,and albumin at 2 and 7 days after surgery were statistically different between the two groups(P<0.01).Conclusion The preoperative albumin and CD4 contents of HIV patients receiving regular HAART treatment were significantly better than those of the non-regular medication group.Patients receiving regular HAART treatment had shorter recovery time of gastrointestinal function after surgery,and liver and kidney function was not significantly interfered during perioperative period.There was no significant difference in wound healing between the two groups.

关 键 词：腹部手术 HIV HAART 

分 类 号：R656[医药卫生—外科学]